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NCT04271527
Non-inferiority Randomized Controlled Trial of Cognitive Targeted Biopsy Versus Software Targeted Biopsy
NA trial testing cognitive fusion targeted biopsy in Prostate Cancer in 626 participants. Currently enrolling.
1 April 2025
Quick facts
| Lead sponsor | Shanghai East Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | diagnostic |
| Enrollment | 626 |
| Start date | 20 February 2024 |
| Primary completion | 1 April 2025 |
| Estimated completion | 14 May 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- cognitive fusion targeted biopsy
Conditions studied
- Prostate Cancer — all drugs for Prostate Cancer →
Sponsor
Shanghai East Hospital
Who can join
18 and older, male only, with Prostate Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomized controlled and non-inferiority trial in comparison of the cognitive fusion targeted biopsy between the software-based fusion targeted biopsy in the detection rate of clinically significant cancer in men suspected to have a PCa.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Study protocol for a single-centre non-inferior randomised controlled trial on a novel three-dimensional matrix positioning-based cognitive fusion-targeted biopsy and software-based fusion-targeted biopsy for the detection rate of clinically significant prostate cancer in men wit
He B, Li R, Li D, Huang L, et al · · 2021 · PMID 33550242 · DOI 10.1136/bmjopen-2020-041427
Verify or expand the search:
- PubMed search for NCT04271527
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Shanghai East Hospital trials
Trials by the same sponsor.
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- NCT07279259 — Thrombolysis in Early Acute Ischemic Stroke Trial-Blood Pressure Management · Phase 2 · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04271527 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai East Hospital
- Last refreshed: 16 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04271527.
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