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NCT04271345
Lung Microbiota Analysis in Critically Ill Patients Admitted to the Intensive Care Unit.
trial in Lung Microbiota in 150 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 15 November 2019 |
| Primary completion | 31 December 2022 |
| Estimated completion | 30 April 2023 |
| Sites | 1 location across Italy |
Conditions studied
- Lung Microbiota — all drugs for Lung Microbiota →
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Who can join
18 and older, any sex, with Lung Microbiota. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our study aims to evaluate the relationship between the heterogeneity of pulmonary microbiota and clinical and outcome variables among critically ill patients admitted to the intensive care unit (ICU). In patients undergoing invasive mechanical ventilation, an aliquot of bronchoalveolar lavage (BAL) fluid will be used in the microbiology laboratory for the analysis of respiratory microbiota through next-generation sequencing technologies and validate computational techniques.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Lung microbiota composition, respiratory mechanics, and outcomes in COVID-19-related ARDS.
De Pascale G, Posteraro B, De Maio F, Pafundi PC, et al · · 2024 · cited 7× · PMID 38466118 · DOI 10.1128/spectrum.03574-23 -
Lung Microbiota Composition, Respiratory Mechanics, and Clinical Outcomes in COVID-19 Patients with ARDS
Pascale GD, Posteraro B, Maio FD, Pafundi PC, et al · · 2023 · DOI 10.2139/ssrn.4316881
Verify or expand the search:
- PubMed search for NCT04271345
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04271345 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Last refreshed: 25 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04271345.
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