NCT04267991 is a clinical trial of Tacrolimus ointment in Corneal Disease, sponsored by Benha University.

Who is sponsoring NCT04267991?

NCT04267991 is sponsored by Benha University.

What drugs are being tested in NCT04267991?

Interventions in NCT04267991: Tacrolimus ointment, phototherapeutic keratectomy.

What condition does NCT04267991 study?

NCT04267991 studies Corneal Disease.

Is NCT04267991 still recruiting?

NCT04267991 is currently completed. Last updated 29 May 2020.

Last reviewed 2020-05-29 · How we verify

NCT04267991

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Corneal Densitometry Changes With Adenoviral SEI

Completed Last updated 29 May 2020

What this trial tests

trial testing Tacrolimus ointment in Corneal Disease in 63 participants. Completed in 15 April 2020.

Timeline

1 April 2018

Primary endpoint
1 April 2020

15 April 2020

Quick facts

Lead sponsor	Benha University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	63
Start date	1 April 2018
Primary completion	1 April 2020
Estimated completion	15 April 2020
Sites	1 location across United Arab Emirates

Drugs / interventions tested

Tacrolimus ointment
phototherapeutic keratectomy

Conditions studied

Corneal Disease — all drugs for Corneal Disease →

Sponsor

Benha University

Who can join

Adults 18 to 75, any sex, with Corneal Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pentacam corneal densitometry-guided treatment of adenoviral corneal subepithelial infiltrates: a comparative study between transepithelial phototherapeutic keratectomy and topical tacrolimus.
Elhamaky TR. · · 2021 · cited 3× · PMID 32852646 · DOI 10.1007/s10792-020-01553-8

Verify or expand the search:

Other trials of Tacrolimus ointment

Trials testing the same drug.

NCT05856994 — Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness Burns · Phase 1 · recruiting
NCT05607901 — A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone · Phase 2 · completed
NCT06035614 — Efficacy and Safety of 308-nm Excimer Lamp Combined With Tacrolimus vs Tacrolimus as Monotherapy in Treating Vitiligo on · NA · completed
NCT04056962 — Tacrolimus for the Treatment of Superficial Kaposiform Hemangioendothelioma and Tufted Angioma · Phase 2 · recruiting
NCT05032248 — Uses of Tacrolimus in Behcet Disease · NA · completed

Other recruiting trials for Corneal Disease

Currently open trials in the same condition.

NCT05573802 — A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethas · Phase 1, PHASE2 · recruiting
NCT06211218 — Artificial Intelligence for Screening of Multiple Corneal Diseases · recruiting
NCT04251143 — Dresden Corneal Disease and Treatment Study · recruiting

Other Benha University trials

Trials by the same sponsor.

NCT07526675 — Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer · NA · not yet recruiting
NCT07480031 — Determination of the Optimal Inspiratory Pressure to Decrease Incidence of Gastric Insufflation With Adequate Ventilatio · NA · not yet recruiting
NCT07465185 — Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery · Phase 2 · recruiting
NCT07467356 — Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip · Phase 3 · recruiting
NCT07300787 — miRNA in Pediatric Gastritis · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04267991 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Benha University
Last refreshed: 29 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04267991.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing