NCT04266288 is a Phase 4 clinical trial of Ketamine in Depression, sponsored by MercyOne Des Moines Medical Center.

Who is sponsoring NCT04266288?

NCT04266288 is sponsored by MercyOne Des Moines Medical Center.

What drugs are being tested in NCT04266288?

Interventions in NCT04266288: Ketamine, Sodium Chloride 0.9%.

What condition does NCT04266288 study?

NCT04266288 studies Depression, Depression Severe, Depression Acute, Depression and Suicide, Suicidal Ideation.

Is NCT04266288 still recruiting?

NCT04266288 is currently completed. Last updated 1 September 2020.

Last reviewed 2020-09-01 · How we verify

NCT04266288

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department

Completed Phase 4 Last updated 1 September 2020

What this trial tests

Phase 4 trial testing Ketamine in Depression in 29 participants. Completed in 31 May 2020.

Timeline

18 October 2019

Primary endpoint
31 May 2020

31 May 2020

Quick facts

Lead sponsor	MercyOne Des Moines Medical Center
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	29
Start date	18 October 2019
Primary completion	31 May 2020
Estimated completion	31 May 2020
Sites	1 location across United States

Drugs / interventions tested

Ketamine (ketamine) — full drug profile →
Sodium Chloride 0.9%

Conditions studied

Depression — all drugs for Depression →
Depression Severe — all drugs for Depression Severe →
Depression Acute — all drugs for Depression Acute →
Depression and Suicide — all drugs for Depression and Suicide →

Sponsor

MercyOne Des Moines Medical Center

Who can join

18 and older, any sex, with Depression or Depression Severe. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to examine the effect of a low-dose ketamine infusion on depression symptoms within the Emergency Department (ED) visit, and healthcare utilization after leaving the ED, when administered in the ED for depression or suicidal ideation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Ketamine

Trials testing the same drug.

NCT05945147 — Ketamine and Midazolam Infusions for CRPS: Feasibility Study · Phase 2 · withdrawn
NCT06963294 — Ketamine and Dexmedetomidine for Delirium in Joint Arthroplasty · NA · not yet recruiting
NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
NCT07197684 — Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surg · NA · not yet recruiting
NCT06231563 — Ketamine for Veterans With Parkinson's Disease · Phase 2 · recruiting

Other recruiting trials for Depression

Currently open trials in the same condition.

NCT07336238 — Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or · Phase 2 · recruiting
NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
NCT07517549 — Sexual Health Education During Pregnancy · NA · recruiting
NCT06408246 — ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression · Phase 2 · recruiting
NCT07449676 — Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression · NA · recruiting

Other MercyOne Des Moines Medical Center trials

Trials by the same sponsor.

NCT04239261 — Serum-derived Bovine Immunoglobulin Effect on Mucositis · Phase 2 · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04266288 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by MercyOne Des Moines Medical Center
Last refreshed: 1 September 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04266288.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing