NCT04266236: LPQLB-SNT

LPB Combined with QLB Using Single-needle Technique (LPQLB-SNT) for Hip Arthroplasty

Completed NA Last updated 10 February 2025

What this trial tests

NA trial testing L3 LPB in Hip Osteoarthritis in 84 participants. Completed in 30 June 2024.

Timeline

9 July 2020

Primary endpoint
31 May 2024

30 June 2024

Quick facts

Lead sponsor	Shanghai 6th People's Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	84
Start date	9 July 2020
Primary completion	31 May 2024
Estimated completion	30 June 2024
Sites	1 location across China

Drugs / interventions tested

• L3 LPB
• L4 LPB
• T12 block
• L3 QLB
• 0.375%ropivacaine 25 ml (Raropin) — full drug profile →
• 0.375%ropivacaine 40 ml (Raropin) — full drug profile →
• General anesthesia with tracheal intubation

Conditions studied

• Hip Osteoarthritis — all drugs for Hip Osteoarthritis →
• Anesthesia, Local — all drugs for Anesthesia, Local →
• Hip Fractures — all drugs for Hip Fractures →
• Osteonecrosis of Femoral Head — all drugs for Osteonecrosis of Femoral Head →

Sponsor

Shanghai 6th People's Hospital

Who can join

Adults 18 to 75, any sex, with Hip Osteoarthritis or Anesthesia, Local. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Total hip arthroplasty (THA) is one of the most successful orthopedic procedures to effectively relieve pain and restore function in patients with hip osteoarthritis, osteonecrosis of femoral head and hip fracture.The Lumbar Plexus Block (LPB) is currently used as the standard regional anesthesia technique to provide postoperative pain management after THA. The lumbar plexus (LP) originates from T12 to L5. In general, multiple-needle nerve blockade procedure is needed to block different branches of LP. Therefore, we need more time to finish the regional anethesia procedure and it's not easy for an inexperienced anesthesiologist to master the technique absolutely. In addition, multiple injections will increase the discomfort of the patients. We aim to investigate the effects of lumbar plexus combined with quadratus lumborum block using single-needle technique with Shamrock method as an alternative regional anesthesia.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. The anesthetic efficacy of ultrasound-guided lumbar plexus combined with quadratus lumborum block with Shamrock approach in total hip arthroplasty: study protocol for a randomized controlled trial.
   Wang X, Zhang H, Chen Y, Xie Z, et al · · 2023 · cited 4× · PMID 37718446 · DOI 10.1186/s13063-023-07619-z
2. Efficacy and safety of combined lumbar plexus and quadratus lumborum block via Shamrock approach at L3 in total hip arthroplasty: a prospective randomized controlled trial.
   Wang X, Zhang J, Xie Z, Chen Y, et al · · 2025 · PMID 41188948 · DOI 10.1186/s13063-025-09195-w