NCT04265924

FIO2 Influences SvO2 Interpretation and Fick-based Cardiac Output Assessment

Completed NA Last updated 17 February 2020

What this trial tests

NA trial testing fraction of inspired oxygen (FIO2) in Cardiac Output in 50 participants. Completed in 30 November 2016.

Timeline

1 December 2015

Primary endpoint
30 November 2016

30 November 2016

Quick facts

Lead sponsor	Chang Gung Memorial Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	50
Start date	1 December 2015
Primary completion	30 November 2016
Estimated completion	30 November 2016

Drugs / interventions tested

• fraction of inspired oxygen (FIO2)

Conditions studied

• Cardiac Output — all drugs for Cardiac Output →

Sponsor

Chang Gung Memorial Hospital

Who can join

20 and older, any sex, with Cardiac Output. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, the investigators sought to clarify the influence of FIO2 levels on the variables in the Fick equation and then assessed the influence of each variable on the accuracy of Fick-CO measurements in patients undergoing cardiac surgery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Increased FIO2 influences SvO2 interpretation and accuracy of Fick-based cardiac output assessment in cardiac surgery patients: A prospective randomized study.
   Lin SY, Chang FC, Lin JR, Chou AH, et al · · 2021 · cited 5× · PMID 34516492 · DOI 10.1097/md.0000000000027020
2. Increased FIO2 Influences SvO2 Interpretation and Accuracy of Fick-based Cardiac Output Assessment in Cardiac Surgery Patients
   Lin S, Chang F, Lin J, Chou A, et al · · 2020 · DOI 10.21203/rs.3.rs-122677/v1