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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults (PREVENTABLE)
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Details
| Lead sponsor | Duke University |
|---|---|
| Phase | PHASE4 |
| Status | RECRUITING |
| Enrolment | 20000 |
| Start date | Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Dec 31 2026 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Cognitive Impairment, Mild
- Dementia
- Cardiovascular Diseases
Interventions
- Atorvastatin 40 Mg Oral Tablet
- Placebo oral tablet
Countries
United States, Puerto Rico