Who is sponsoring NCT04257942?

NCT04257942 is sponsored by Sheba Medical Center.

What drugs are being tested in NCT04257942?

Interventions in NCT04257942: carotid endarterectomy.

What condition does NCT04257942 study?

NCT04257942 studies Crystallization of Cholesterol in Atherosclerosis.

Is NCT04257942 still recruiting?

NCT04257942 is currently status unknown. Last updated 6 February 2020.

Last reviewed 2020-02-06 · How we verify

NCT04257942

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pathological Crystallization of Cholesterol in Atherosclerosis

Status unknown Last updated 6 February 2020

What this trial tests

trial testing carotid endarterectomy in Crystallization of Cholesterol in Atherosclerosis in 50 participants. Status unknown.

Timeline

1 May 2020

Primary endpoint
1 May 2020

30 June 2021

Quick facts

Lead sponsor	Sheba Medical Center
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	50
Start date	1 May 2020
Primary completion	1 May 2020
Estimated completion	30 June 2021

Drugs / interventions tested

carotid endarterectomy

Conditions studied

Crystallization of Cholesterol in Atherosclerosis — all drugs for Crystallization of Cholesterol in Atherosclerosis →

Sponsor

Sheba Medical Center

Who can join

Eligibility, any sex, with Crystallization of Cholesterol in Atherosclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Endarterectomy of the carotid artery procedure will be performed at Sheba Medical center vascular surgery department, followed by fixation and histology. Tissues will then be transferred to Weizmann Institute of Science for observation implementing advanced electron microscopy techniques. Finally, joint evaluation of the results will be carried out, in relation to the patient clinical history.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

3D cryoimaging of cell-mediated cholesterol crystal clearance in human atherosclerotic lesions.
Capua-Shenkar J, Kaestner A, Rechav K, Brumfeld V, et al · · 2025 · PMID 40911589 · DOI 10.1073/pnas.2510133122

Verify or expand the search:

Other trials of carotid endarterectomy

Trials testing the same drug.

NCT07054060 — Endarterectomy Versus Stenting in Patients With Symptomatic Severe Carotid Stenosis - 2 · NA · recruiting
NCT07083986 — Carotid Endarterectomy Versus Stenting in Patients With Acute Stage of Ischemic Stroke. · NA · enrolling by invitation
NCT06175715 — General Versus Regional Anesthesia for Carotid Endarterectomy at Acute Ischemic Stroke Trial · NA · recruiting
NCT04847752 — Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis · recruiting
NCT04955015 — Associations of Carotid Plaque Characteristics With Brain Perfusion and Cognitive Function in Patients Undergoing CEA · unknown

Other Sheba Medical Center trials

Trials by the same sponsor.

NCT07401524 — Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage · Phase 4 · not yet recruiting
NCT07523373 — Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch · NA · not yet recruiting
NCT07509229 — 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients · Phase 1, PHASE2 · not yet recruiting
NCT07405723 — Arm Position and Blood Pressure Measurement Accuracy During Pregnancy · NA · recruiting
NCT07474987 — Portable VR-based Chromatic Pupilloperimeter for Diagnosis and Monitoring of Traumatic Brain Injury · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04257942 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sheba Medical Center
Last refreshed: 6 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04257942.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing