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NCT04256135: MulliganKnee
Manual Therapy on Activation of the Descending Pain Inhibitory System in Patients With Knee Osteoarthritis
NA trial testing Mulligan mobilization in Musculoskeletal Manipulations in 28 participants. Completed in 10 June 2020.
15 May 2020
Quick facts
| Lead sponsor | Universidad Rey Juan Carlos |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 28 |
| Start date | 30 April 2020 |
| Primary completion | 15 May 2020 |
| Estimated completion | 10 June 2020 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Mulligan mobilization
- AP Maitland mobilization
Conditions studied
- Musculoskeletal Manipulations — all drugs for Musculoskeletal Manipulations →
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Sponsor
Universidad Rey Juan Carlos — full company profile →
Who can join
65 and older, any sex, with Musculoskeletal Manipulations or Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Knee osteoarthritis is a clinical syndrome which is characterized by pain. It has been shown to cause changes in the nervous system leading to central sensitization. There are factors involved in this disease such as sex (female) or obesity. The most recommended therapy is physical therapy, but manual therapy is needed to cause changes in central sensitization. Methods: Experimental, prospective, parallel and longitudinal double-blind study, in which two groups are performed: group A (AP mobilizations) and group B (Mulligan's mobilizations). Different variables and questionnaires were used: pressure pain threshold, temporal summation, pain modulation, central sensitization inventory, WOMAC, Times Up \& GO, numerical rating scale, Beck, STAI, kinesiophobia, catastrophism, Barthel and mini- cognitive test
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04256135
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mulligan mobilization
Trials testing the same drug.
- NCT07383038 — Effect of Mobilization With Movement in Patients With Rotator Cuff Lesions · NA · recruiting
- NCT07029113 — Effects of Task-Oriented Training and Mulligan Mobilization on Hand Function, Pain and Quality of Life in Patients With · NA · completed
- NCT07310810 — Mulligan Mobilization vs Shockwave Therapy in Adhesive Capsulitis · NA · active not recruiting
- NCT06357624 — Effectiveness of Mulligan Mobilization Technique · NA · completed
- NCT05347537 — Effects of Mulligan's Mobilization With and Without Clamshell Exercises in Sacroiliac Joint Dysfunction · NA · completed
Other Universidad Rey Juan Carlos trials
Trials by the same sponsor.
- NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
- NCT07402902 — Caffeine Strategies and Fat Oxidation · NA · not yet recruiting
- NCT07251738 — Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease · not yet recruiting
- NCT07247760 — PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE · NA · enrolling by invitation
- NCT06968676 — Mixed Reality for Upper Limb Rehabilitation in People With Multiple Sclerosis (VIRTUALDOMUS) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04256135 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Rey Juan Carlos
- Last refreshed: 27 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04256135.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing