NCT04255524 is a NA clinical trial of Optic coherence tomography angiography (OCTA) in Myopia, Progressive, sponsored by The First Affiliated Hospital with Nanjing Medical University.

Who is sponsoring NCT04255524?

NCT04255524 is sponsored by The First Affiliated Hospital with Nanjing Medical University.

What drugs are being tested in NCT04255524?

Interventions in NCT04255524: Optic coherence tomography angiography (OCTA).

What condition does NCT04255524 study?

NCT04255524 studies Myopia, Progressive, Choroid Disease.

Is NCT04255524 still recruiting?

NCT04255524 is currently not yet recruiting. Last updated 5 February 2020.

Last reviewed 2020-02-05 · How we verify

NCT04255524

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Choroidal Change on OCTA in Eyes With High Myopia

Not yet recruiting NA Last updated 5 February 2020

What this trial tests

NA trial testing Optic coherence tomography angiography (OCTA) in Myopia, Progressive in 200 participants. Not yet recruiting.

Timeline

1 February 2020

Primary endpoint
31 December 2030

31 December 2030

Quick facts

Lead sponsor	The First Affiliated Hospital with Nanjing Medical University
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	200
Start date	1 February 2020
Primary completion	31 December 2030
Estimated completion	31 December 2030
Sites	1 location across China

Drugs / interventions tested

Optic coherence tomography angiography (OCTA)

Conditions studied

Myopia, Progressive — all drugs for Myopia, Progressive →
Choroid Disease — all drugs for Choroid Disease →

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Who can join

Adults 18 to 55, any sex, with Myopia, Progressive or Choroid Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Myopia is a global healthy concern, especially the high myopia and pathological myopia among Asian populations. However, its mechanism still remains largely unclear. Recent findings suggested choroidal changes might be related to the development of myopia. This study is to useOCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature change in myopic eyes, and try to find the cause-and-effect relationship between choroidal change and the development of myopia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Microvascular Alterations of Peripapillary Choriocapillaris in Young Adult High Myopia Detected by Optical Coherence Tomography Angiography.
Lei J, Fan Y, Wu Y, Yuan S, et al · · 2023 · cited 4× · PMID 36836523 · DOI 10.3390/jpm13020289

Verify or expand the search:

Other recruiting trials for Myopia, Progressive

Currently open trials in the same condition.

NCT06927388 — Myopia Progression With Freeform Myopia Control Spectacles · NA · active not recruiting
NCT07055815 — Impact of Digital Screen Time in Progression of Myopia in Children · active not recruiting
NCT06389110 — Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elo · Phase 3 · recruiting
NCT06647160 — Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control · NA · active not recruiting
NCT06520124 — Stellest Lens Wear in Adult Progressing Myopes · NA · active not recruiting

Other The First Affiliated Hospital with Nanjing Medical University trials

Trials by the same sponsor.

NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
NCT07523789 — Comparison of Chemotherapy and Immunotherapy in Neoadjuvant Therapy for TNBC · not yet recruiting
NCT07464756 — SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer · Phase 2 · not yet recruiting
NCT07482826 — Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis · NA · not yet recruiting
NCT07558863 — Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04255524 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
Last refreshed: 5 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04255524.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing