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NCT04254250
Preoperative Estimation Of Disc Herniation Recurrence In Patients With Lumbar Disc Herniation
trial testing Preoperative risk estimation of disc herniation recurrence in Intervertebral Disc Herniation in 386 participants. Completed in 25 February 2026.
10 August 2023
Quick facts
| Lead sponsor | Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 386 |
| Start date | 10 February 2020 |
| Primary completion | 10 August 2023 |
| Estimated completion | 25 February 2026 |
| Sites | 2 locations across Russia |
Drugs / interventions tested
- Preoperative risk estimation of disc herniation recurrence
Conditions studied
- Intervertebral Disc Herniation — all drugs for Intervertebral Disc Herniation →
Sponsor
Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan
Who can join
Adults 18 to 60, any sex, with Intervertebral Disc Herniation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will be conducted at Research Institute of Traumatology and Orthopedics (NRITO) n.a. Ya.L.Tsivyan, Novosibirsk, Russia. The current study is prospective observational study to evaluate the efficacy of preoperative estimation of disc herniation recurrence among patients with lumbar disc herniation using predictive mathematical model at terms 3 years postoperatively . It is expected to enroll 350 patients aged 18-70 with lumbar disc herniation. Risk estimation of disc herniation recurrence will be evaluated preoperatively, then patient will undergo conventional microdiscectomy. Postoperative eximanation will include Visits every 6-months during 3 years to evaluate clinical outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04254250
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan trials
Trials by the same sponsor.
- NCT04408846 — Minimally Invasive Surgery Versus Traditional Open Surgery In The Treatment Of Single Level Lumbar Stenosis · NA · withdrawn
- NCT03908203 — Minimally Invasive Surgery Techniques for One-level Degenerative Lumbar Deformities Correction · NA · withdrawn
- NCT03748277 — Comparison of Open and Minimally Invasive Surgical Techniques in the Treatment of Degenerative One-level Stenosis of Lum · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04254250 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Novosibirsk Research Institute of Traumatology and Orthopaedics n.a. Ya.L. Tsivyan
- Last refreshed: 27 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04254250.
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