NCT04252677 (HL-Squared) is a NA clinical trial of Obesity Prevention in Obesity, Adolescent, sponsored by City University of New York, School of Public Health.

Who is sponsoring NCT04252677?

NCT04252677 is sponsored by City University of New York, School of Public Health.

What drugs are being tested in NCT04252677?

Interventions in NCT04252677: Obesity Prevention, Health Literacy.

What condition does NCT04252677 study?

NCT04252677 studies Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy, Exercise, Health Literacy.

Is NCT04252677 still recruiting?

NCT04252677 is currently completed. Last updated 12 February 2025.

Last reviewed 2025-02-12 · How we verify

NCT04252677: HL-Squared

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Health Literacy and Obesogenic Behaviors

Completed NA Last updated 12 February 2025

What this trial tests

NA trial testing Obesity Prevention in Obesity, Adolescent in 36 participants. Completed in 30 December 2024.

Timeline

16 November 2022

Primary endpoint
30 December 2024

30 December 2024

Quick facts

Lead sponsor	City University of New York, School of Public Health
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	36
Start date	16 November 2022
Primary completion	30 December 2024
Estimated completion	30 December 2024
Sites	1 location across United States

Drugs / interventions tested

Obesity Prevention
Health Literacy

Conditions studied

Obesity, Adolescent — all drugs for Obesity, Adolescent →
Health Behavior — all drugs for Health Behavior →
Health Knowledge, Attitudes, Practice — all drugs for Health Knowledge, Attitudes, Practice →
Diet, Healthy — all drugs for Diet, Healthy →

Sponsor

City University of New York, School of Public Health

Who can join

Adults 13 to 17, any sex, with Obesity, Adolescent or Health Behavior. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prevalence of adolescent behaviors that can lead to obesity are alarming, and reduced life expectancy is the future of America's youth if behavioral changes are not implemented to improve health and reduce the obesity burden. Researchers have argued that health literacy is a precursor to health knowledge and is necessary for translating knowledge about healthy choices into behavior, with low health literacy being associated with reduced preventive health behaviors in adults. Given the lack of health literacy-specific interventions addressing adolescents' obesogenic behaviors, the purpose of this study is to examine the preliminary effectiveness of adding a health literacy module to an obesity prevention intervention that addresses adolescents' obesogenic behaviors.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Interventions to prevent obesity in children aged 2 to 4 years old.
Phillips SM, Spiga F, Moore TH, Dawson S, et al · · 2025 · cited 3× · PMID 40494564 · DOI 10.1002/14651858.cd015326.pub2
A Web-Based Intervention to Improve Health Literacy and Obesogenic Behaviors Among Adolescents: Protocol of a Randomized Pilot Feasibility Study for a Parallel Randomized Controlled Trial.
Fleary SA. · · 2022 · cited 2× · PMID 35972787 · DOI 10.2196/40191

Verify or expand the search:

Other trials of Obesity Prevention

Trials testing the same drug.

NCT03529695 — In-home Obesity Prevention to Reach Low-income Infants · NA · completed

Other recruiting trials for Obesity, Adolescent

Currently open trials in the same condition.

NCT06920862 — Multi-Modal Digital Interventions for Adolescent Weight Management · NA · recruiting
NCT06822387 — Health Without Barriers/Salud Sin Barreras- Northern Colorado · NA · recruiting
NCT06309121 — Effects of the Postbiotic Blend ABB C3 on Adiposity and Glucose Metabolism in Children and Adolescents · NA · active not recruiting
NCT05982847 — National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa · recruiting
NCT06515288 — Nutrition Goes to School: a School-based Nutrition Intervention to Promote Healthy Eating Behaviour Among Adolescents · NA · recruiting

Other City University of New York, School of Public Health trials

Trials by the same sponsor.

NCT06119854 — Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression · NA · completed
NCT06970652 — Virtual Reality (VR) for Stress Management · NA · completed
NCT05833555 — Harlem Strong Mental Health Coalition · NA · recruiting
NCT05714280 — PA4Health Physical Activity App Open Pilot Study for African American Women · NA · active not recruiting
NCT04491045 — Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04252677 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by City University of New York, School of Public Health
Last refreshed: 12 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04252677.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing