NCT04251949 (MuciLight) is a Phase 2 clinical trial of LED photobiomodulation in Oral Cancer, sponsored by Centre Oscar Lambret.

Who is sponsoring NCT04251949?

NCT04251949 is sponsored by Centre Oscar Lambret.

What drugs are being tested in NCT04251949?

Interventions in NCT04251949: LED photobiomodulation.

What condition does NCT04251949 study?

NCT04251949 studies Oral Cancer, Oropharyngeal Cancer.

Is NCT04251949 still recruiting?

NCT04251949 is currently completed. Last updated 18 March 2026.

Last reviewed 2026-03-18 · How we verify

NCT04251949: MuciLight

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Photobiomodulation Using LED Lamp for Curative Treatment of Radio-induced Mucositis.

Completed Phase 2 Last updated 18 March 2026

What this trial tests

Phase 2 trial testing LED photobiomodulation in Oral Cancer in 28 participants. Completed in 19 September 2022.

Timeline

19 March 2021

Primary endpoint
19 September 2022

19 September 2022

Quick facts

Lead sponsor	Centre Oscar Lambret
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	28
Start date	19 March 2021
Primary completion	19 September 2022
Estimated completion	19 September 2022
Sites	1 location across France

Drugs / interventions tested

LED photobiomodulation

Conditions studied

Oral Cancer — all drugs for Oral Cancer →
Oropharyngeal Cancer — all drugs for Oropharyngeal Cancer →

Sponsor

Centre Oscar Lambret — full company profile →

Who can join

18 and older, any sex, with Oral Cancer or Oropharyngeal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a monocentric, prospective, non-comparative phase II study with minimal risks and constraints. The study will aim to assess the curative treatment of radio-induced mucositis by photobiomodulation using LED lamp.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Ionizing radiation: molecular mechanisms, biological effects, and therapeutic targets.
Wei W, Ren Y, Lan J, Yi J, et al · · 2026 · PMID 41507636 · DOI 10.1186/s43556-025-00358-4

Verify or expand the search:

Other trials of LED photobiomodulation

Trials testing the same drug.

NCT04424823 — LED Photobiomodulation Therapy for Non-specific LBP in Working Nurses · NA · unknown
NCT03696706 — Photobiomodulation With Red and Infrared LED Device for Temporomandibular Dysfunction · Phase 2 · unknown

Other recruiting trials for Oral Cancer

Currently open trials in the same condition.

NCT07509619 — AI-based Physiotherapy Evaluation System for Range of Motion in Oral Cancer Patients · recruiting
NCT07260344 — Evaluation of Two Non-Invasive Methods, High-Resolution Microendoscopy and Liquid-Based Cytology, for Detection of Oral · NA · recruiting
NCT06682494 — Enhancing Oral Cancer Awareness · NA · recruiting
NCT07095608 — Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain · NA · recruiting
NCT07296250 — Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT · NA · recruiting

Other Centre Oscar Lambret trials

Trials by the same sponsor.

NCT07507773 — Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the · Phase 2 · not yet recruiting
NCT06807164 — Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome · Phase 2 · recruiting
NCT06969833 — Prospective Clinico-biological Database of Patients With Ovarian and/or Peritoneal and/or Fallopian Tube Carcinoma · NA · recruiting
NCT06181201 — Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer · terminated
NCT05286684 — Feasibility of Exosome Analysis in Cerebrospinal Fluid During the Diagnostic Workup of Metastatic Meningitis · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04251949 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Oscar Lambret
Last refreshed: 18 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04251949.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing