NCT04251273

Text Message Quit Vaping Intervention for Young Adults

Completed NA Results posted Last updated 10 July 2024

What this trial tests

NA trial testing This is Quitting in Tobacco Cessation in 2,588 participants. Completed in 12 November 2020.

Timeline

19 December 2019

Primary endpoint
12 November 2020

12 November 2020

Quick facts

Lead sponsor	Truth Initiative
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	2,588
Start date	19 December 2019
Primary completion	12 November 2020
Estimated completion	12 November 2020
Sites	1 location across United States

Drugs / interventions tested

• This is Quitting
• Assessment only Control

Conditions studied

• Tobacco Cessation — all drugs for Tobacco Cessation →

Sponsor

Truth Initiative

Who can join

Adults 18 to 24, any sex, with Tobacco Cessation. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants With Self-reported 30-day Point Prevalence Abstinence (ITT) Primary · 7 months post enrollment

Number of participant who responded "No" to the question "In the past 30 days, did you vape at all, even a puff of someone else's?" Denominator is all randomized participants.

Group	Value	95% CI
This is Quitting	314
Assessment Only Control	239

Number of Participants With Self-reported 30-day Point Prevalence Abstinence (Responder Only) Secondary · 7 month post enrollment

Number of participants with who responded 'No" to the question "In the past 30 days, did you vape at all, even a puff of someone else's?" Denominator is participants with responses only.

Group	Value	95% CI
This is Quitting	314
Assessment Only Control	239

Number of Participants With Self-reported 7-day Point Prevalence Abstinence (ITT) Secondary · 7 months post enrollment

Number of participants who responded "No" to the question "Have you used any vape, even one puff, in the past 7 days?" Denominator is all randomized participants.

Group	Value	95% CI
This is Quitting	440
Assessment Only Control	385

Number of Participants With Self-reported 7-day Point Prevalence Abstinence (Responder Only) Secondary · 7 months post enrollment

Number of participants who responded "No" to the question "Have you used any vape, even one puff, in the past 7 days?" Denominator is those who responded to the question only.

Group	Value	95% CI
This is Quitting	440
Assessment Only Control	385

Sponsor's own description

This research study, conducted by Truth Initiative, will help us learn how text messaging can help young adults between 18 and 24 years of age quit vaping.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Effectiveness of a Vaping Cessation Text Message Program Among Young Adult e-Cigarette Users: A Randomized Clinical Trial.
   Graham AL, Amato MS, Cha S, Jacobs MA, et al · · 2021 · cited 115× · PMID 33999133 · DOI 10.1001/jamainternmed.2021.1793
2. Effectiveness of a Quit Vaping Text Message Program in Promoting Abstinence Among Young Adult E-Cigarette Users: Protocol for a Randomized Controlled Trial.
   Graham AL, Jacobs MA, Amato MS, Cha S, et al · · 2020 · cited 28× · PMID 32356774 · DOI 10.2196/18327
3. Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation.
   Graham AL, Cha S, Do EK, Jacobs MA, et al · · 2025 · PMID 41177894 · DOI 10.1186/s13011-025-00679-1