NCT04251091 is a NA clinical trial of Treadmill walking in Stroke, sponsored by Arun Jayaraman, PT, PhD.

Who is sponsoring NCT04251091?

NCT04251091 is sponsored by Arun Jayaraman, PT, PhD.

What drugs are being tested in NCT04251091?

Interventions in NCT04251091: Treadmill walking, Overground Walking.

Is NCT04251091 still recruiting?

NCT04251091 is currently active, enrolled. Last updated 1 April 2025.

Last reviewed 2025-04-01 · How we verify

NCT04251091

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ankle Exosuit Training in the Clinic to Community Community

Active, enrolled NA Last updated 1 April 2025

What this trial tests

NA trial testing Treadmill walking in Stroke in 10 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

10 January 2020

Primary endpoint
31 December 2025

31 December 2025

Quick facts

Lead sponsor	Arun Jayaraman, PT, PhD
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	10 January 2020
Primary completion	31 December 2025
Estimated completion	31 December 2025
Sites	1 location across United States

Drugs / interventions tested

Treadmill walking
Overground Walking

Conditions studied

Stroke — all drugs for Stroke →

Sponsor

Arun Jayaraman, PT, PhD

Who can join

Adults 18 to 80, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study focuses on investigating exosuit technology by evaluating its ability to provide a gait-restorative effect delivered in both clinic and community settings. The exosuit provides dynamic dorsiflexion and plantarflexion assist during walking. We will determine the effect of training parameters of intensity, repetition, and gait quality which are all key parameters associated with experience-dependent neuroplasticity. The other objective is to determine the effect of this intervention on community walking activity, walking speed, walking distance, and locomotor mechanics and energetics.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Soft robotic exosuit augmented high intensity gait training on stroke survivors: a pilot study.
Shin SY, Hohl K, Giffhorn M, Awad LN, et al · · 2022 · cited 18× · PMID 35655180 · DOI 10.1186/s12984-022-01034-2

Verify or expand the search:

Other trials of Treadmill walking

Trials testing the same drug.

NCT06260735 — Non-invasive Spinal Cord Stimulation After Spinal Cord Injury · NA · unknown
NCT04284436 — Study in Parkinson Disease of Exercise · NA · recruiting
NCT04733222 — Effect of Treadmill Perturbation Training on Falls · NA · completed
NCT03484624 — Effect of Wearable Hip-Assist Robot on Reduction of Cardiopulmonary Metabolic Efficiency in Healthy Adults · NA · completed

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07356011 — Exoskeleton for Balance · NA · recruiting
NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other Arun Jayaraman, PT, PhD trials

Trials by the same sponsor.

NCT05334680 — International Validation of Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04251091 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Arun Jayaraman, PT, PhD
Last refreshed: 1 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04251091.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing