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NCT04249869
The Efficacy of Traditional Chinese Herbal Medicine for Alzheimer's Disease
Phase 1, PHASE2 trial testing VGH-AD1 in Alzheimer Disease in 28 participants. Status unknown.
31 December 2020
Quick facts
| Lead sponsor | Taipei Veterans General Hospital, Taiwan |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 28 |
| Start date | 1 February 2020 |
| Primary completion | 31 December 2020 |
| Estimated completion | 31 December 2020 |
Drugs / interventions tested
- VGH-AD1 — full drug profile →
Conditions studied
- Alzheimer Disease — all drugs for Alzheimer Disease →
Sponsor
Taipei Veterans General Hospital, Taiwan
Who can join
65 and older, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized, double-blinded, placebo-controlled, crossover clinical trial aims to investigate the effect of VGH-AD1, a scientific Chinese medicine powder prescription, on patients with Alzheimer's disease.
Publications & conference data
7 peer-reviewed publications reference this trial (live from Europe PMC):
-
Alzheimer's disease drug development pipeline: 2022.
Cummings J, Lee G, Nahed P, Kambar MEZN, et al · · 2022 · cited 369× · PMID 35516416 · DOI 10.1002/trc2.12295 -
Alzheimer's disease drug development pipeline: 2020.
Cummings J, Lee G, Ritter A, Sabbagh M, et al · · 2020 · cited 350× · PMID 32695874 · DOI 10.1002/trc2.12050 -
Alzheimer's disease drug development pipeline: 2021.
Cummings J, Lee G, Zhong K, Fonseca J, et al · · 2021 · cited 312× · PMID 34095440 · DOI 10.1002/trc2.12179 -
Therapeutic approaches for improving cognitive function in the aging brain.
Chen L, Jiao J, Zhang Y. · · 2022 · cited 26× · PMID 36570840 · DOI 10.3389/fnins.2022.1060556 -
Combining human and machine intelligence for clinical trial eligibility querying.
Fang Y, Idnay B, Sun Y, Liu H, et al · · 2022 · cited 21× · PMID 35426943 · DOI 10.1093/jamia/ocac051 -
Natural Products from Plants and Algae for Treatment of Alzheimer's Disease: A Review.
Klose J, Griehl C, Roßner S, Schilling S. · · 2022 · cited 7× · PMID 35625622 · DOI 10.3390/biom12050694 -
Recent advancements in the role of phytochemicals and medicinal plants in prophylaxis and management of Alzheimer's disease.
Mishra A, Krishnamurthy S. · · 2024 · PMID 39386232 · DOI 10.22038/ijbms.2024.77760.16826
Verify or expand the search:
- PubMed search for NCT04249869
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04249869 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Veterans General Hospital, Taiwan
- Last refreshed: 31 January 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04249869.
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