Who is sponsoring NCT04246216?

NCT04246216 is sponsored by Universidad Rey Juan Carlos.

What drugs are being tested in NCT04246216?

Interventions in NCT04246216: Percutaneous Electrical Nerve Stimulation, Endoscopic surgery of the carpal tunnel.

What condition does NCT04246216 study?

NCT04246216 studies Carpal Tunnel Syndrome.

Is NCT04246216 still recruiting?

NCT04246216 is currently completed. Last updated 8 February 2023.

Last reviewed 2023-02-08 · How we verify

NCT04246216

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Percutaneous Electrical Nerve Stimulation for Carpal Tunnel Syndrome

Completed NA Last updated 8 February 2023

What this trial tests

NA trial testing Percutaneous Electrical Nerve Stimulation in Carpal Tunnel Syndrome in 70 participants. Completed in 31 March 2022.

Timeline

1 March 2020

Primary endpoint
31 March 2021

31 March 2022

Quick facts

Lead sponsor	Universidad Rey Juan Carlos
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	70
Start date	1 March 2020
Primary completion	31 March 2021
Estimated completion	31 March 2022
Sites	1 location across Spain

Drugs / interventions tested

Percutaneous Electrical Nerve Stimulation
Endoscopic surgery of the carpal tunnel

Conditions studied

Carpal Tunnel Syndrome — all drugs for Carpal Tunnel Syndrome →

Sponsor

Universidad Rey Juan Carlos — full company profile →

Who can join

Adults 18 to 65, female only, with Carpal Tunnel Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is evidence supporting that physical therapy interventions can be effective for the management of patients with CTS. No consensus on the best approach exist. It seems clear that the median nerve is affected in several ways (compression, inflammation, excursion) in carpal tunnel syndrome. Percutaneous Electrical Nerve Stimulation is a treatment approach consisting of the application of an electrical current throughout needling filaments placed close to the nerve, in this case the median nerve. The purpose of this clinical trial is to compare changes in function, symptom severity and the intensity of pain after the application of Percutaneous Electrical Nerve Stimulation vs. endoscopic surgery in women with CTS at short- and long-term follow-up periods.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Surgical versus non-surgical treatment for carpal tunnel syndrome.
Lusa V, Karjalainen TV, Pääkkönen M, Rajamäki TJ, et al · · 2024 · cited 9× · PMID 38189479 · DOI 10.1002/14651858.cd001552.pub3
Peripheral Nerve Stimulation in Painful Conditions of the Upper Extremity-An Overview.
Yaccarino V, Jin MY, Abd-Elsayed A, Kraemer JM, et al · · 2022 · cited 9× · PMID 36359295 · DOI 10.3390/biomedicines10112776
Ultrasound-guided percutaneous electrical nerve stimulation versus surgery for women with unilateral carpal tunnel syndrome: A randomized parallel-group trial.
Fernández-de-Las-Peñas C, Ortega-Santiago R, De-la-Llave-Rincón AI, Cleland JA, et al · · 2023 · cited 4× · PMID 36987682 · DOI 10.1002/ejp.2117

Verify or expand the search:

Other trials of Percutaneous Electrical Nerve Stimulation

Trials testing the same drug.

NCT06158568 — Percutaneous Electrical Nerve Stimulation and Exercise for Shoulder Pain · NA · completed
NCT05432973 — Percutaneous Electrical Nerve Stimulation Compared to Passive Assisted Neurodynamics in Brachial Plexus Neuropathy · NA · unknown

Other recruiting trials for Carpal Tunnel Syndrome

Currently open trials in the same condition.

NCT07312123 — A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome · NA · recruiting
NCT07334964 — Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method · NA · recruiting
NCT07414069 — High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological Outcomes · NA · recruiting
NCT07114913 — Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome · recruiting
NCT06905769 — Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient · NA · active not recruiting

Other Universidad Rey Juan Carlos trials

Trials by the same sponsor.

NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
NCT07402902 — Caffeine Strategies and Fat Oxidation · NA · not yet recruiting
NCT07251738 — Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease · not yet recruiting
NCT07247760 — PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE · NA · enrolling by invitation
NCT06968676 — Mixed Reality for Upper Limb Rehabilitation in People With Multiple Sclerosis (VIRTUALDOMUS) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04246216 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad Rey Juan Carlos
Last refreshed: 8 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04246216.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing