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NCT04245605: ICE-HF
Invasive Coronary Angiography Early in Ischemic Heart Failure
trial testing Coronary angiography in Acute Heart Failure in 2,994 participants. Completed in 30 September 2021.
31 March 2015
Quick facts
| Lead sponsor | Institute for Clinical Evaluative Sciences |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 2,994 |
| Start date | 1 April 2010 |
| Primary completion | 31 March 2015 |
| Estimated completion | 30 September 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Coronary angiography
Conditions studied
- Acute Heart Failure — all drugs for Acute Heart Failure →
Sponsor
Institute for Clinical Evaluative Sciences
Who can join
18 and older, any sex, with Acute Heart Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Early invasive coronary angiography and acute ischaemic heart failure outcomes.
Kosyakovsky LB, Austin PC, Ross HJ, Wang X, et al · · 2021 · cited 16× · PMID 34331056 · DOI 10.1093/eurheartj/ehab423
Verify or expand the search:
- PubMed search for NCT04245605
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Coronary angiography
Trials testing the same drug.
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- NCT06182683 — Concurrent OCT and FFR-guided PCI in CAD · NA · recruiting
- NCT05725616 — Effectiveness of the Anatomical Snuff Box Approach for Coronary Angiography · NA · completed
- NCT05184426 — MuLtimodality EvaluatiOn of aNtibody mEdiated Damage in Heart Transplantation (LEONE-HT) · active not recruiting
Other recruiting trials for Acute Heart Failure
Currently open trials in the same condition.
- NCT06587854 — a PRagmatic Observational Study of Congestion proFILes in patiEnts With Acute Heart Failure · recruiting
- NCT07008365 — The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure · Phase 3 · recruiting
- NCT06465498 — Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography · NA · recruiting
- NCT06597331 — Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital · recruiting
- NCT06166654 — Optimal Diuretic Therapies for Acute Heart Failure With Volume Overload · Phase 4 · recruiting
Other Institute for Clinical Evaluative Sciences trials
Trials by the same sponsor.
- NCT04067297 — Using Big Data to Conduct Innovative Cardiovascular Clinical Trials · NA · active not recruiting
- NCT05028686 — Predicting Readmissions Using Omics, Biostatistical Evaluate and Artificial Intelligence · recruiting
- NCT04187742 — Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase · NA · completed
- NCT03807466 — Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04245605 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institute for Clinical Evaluative Sciences
- Last refreshed: 29 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04245605.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing