Last reviewed · How we verify
NCT04241328: SYMBIOSIS
Medtronic SYMBIOSIS Post-Market Registry for Patients Undergoing Cardiac Surgery
trial in Cardiovascular Diseases in 5,000 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Medtronic Cardiac Surgery |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 5,000 |
| Start date | 9 January 2020 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 14 locations across France, Netherlands, Greece, Belgium, Austria, Germany, Norway, Spain |
Conditions studied
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
Medtronic Cardiac Surgery — full company profile →
Who can join
Eligibility, any sex, with Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this observational, multi-center prospective, post-market registry is to confirm real-world device safety and performance, to ensure the continued acceptability of identified risks, and detect emerging risks.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04241328
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07324278 — Hybrid Stroke Rehab With Mirror Priming · NA · recruiting
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Other Medtronic Cardiac Surgery trials
Trials by the same sponsor.
- NCT04073420 — Medtronic Cardiac Surgery PMCF Registry · recruiting
- NCT03139721 — Medtronic HAMMOCK Post Approval Study · completed
- NCT03283722 — PRESERVE-MITRAL Post-Market Registry · completed
- NCT02088554 — PERIGON Pivotal Trial · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04241328 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medtronic Cardiac Surgery
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04241328.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing