Last reviewed · How we verify
NCT04240561
Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia
NA trial testing High level of signal manipulation in Hearing Loss, Sensorineural in 20 participants. Currently enrolling.
31 August 2025
Quick facts
| Lead sponsor | Northwestern University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 July 2021 |
| Primary completion | 31 August 2025 |
| Estimated completion | 31 August 2025 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- High level of signal manipulation
- Low level of signal manipulation
Conditions studied
- Hearing Loss, Sensorineural — all drugs for Hearing Loss, Sensorineural →
- Dementia of Alzheimer Type — all drugs for Dementia of Alzheimer Type →
- Amnestic Mild Cognitive Impairment — all drugs for Amnestic Mild Cognitive Impairment →
Sponsor
Northwestern University
Who can join
Adults 50 to 90, any sex, with Hearing Loss, Sensorineural or Dementia of Alzheimer Type. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This current translational project, funded by NIH, aims to better understand the impact of various signal modification strategies for older adults with Alzheimer's dementia and its potential precursor, known as amnestic mild cognitive impairment. The investigators hypothesize that adults with Alzheimer's dementia represent an extreme case of restricted cognitive ability, such that very low working memory capacity and overall reduced cognitive capacity will limit benefit from advanced signal processing. Thus, the investigators hypothesize that adults with Alzheimer's dementia will receive greater benefit from acoustically simple, high-fidelity hearing aid processing that minimally alters the acoustic signal.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04240561
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hearing Loss, Sensorineural
Currently open trials in the same condition.
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- NCT06560918 — Self-efficacy-based Auditory Rehabilitation With Over-the-Counter Hearing Aids · NA · recruiting
- NCT06882889 — Comparing the Efficacy of Domestic Versus Imported Hearing Aids in ARHL · NA · recruiting
- NCT06664697 — Post-Market Clinical Investigation of the IotaSOFT Insertion System · recruiting
- NCT06268340 — Hearing and Structure Preservation Via ECochG · NA · recruiting
Other Northwestern University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04240561 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwestern University
- Last refreshed: 15 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04240561.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing