Last reviewed · How we verify
NCT04240522: ProRaD
Prospective Longitudinal Observational Research in Atopic Dermatitis
trial in Atopic Dermatitis in 1,000 participants. Currently enrolling.
30 March 2031
Quick facts
| Lead sponsor | University of Zurich |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 4 April 2017 |
| Primary completion | 30 March 2031 |
| Estimated completion | 30 March 2031 |
| Sites | 1 location across Switzerland |
Conditions studied
- Atopic Dermatitis — all drugs for Atopic Dermatitis →
- Asthma — all drugs for Asthma →
- Atopic Dermatitis and Related Conditions — all drugs for Atopic Dermatitis and Related Conditions →
Sponsor
University of Zurich
Who can join
Adults 1 to 85, any sex, with Atopic Dermatitis or Asthma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march. Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition. However, the underlying factors such as genetic phenotype, environmental factors, or life style which cause or worsen an existing allergic disease are not understood yet. Affected people suffer from recurrent flares that result in significantly impaired quality. This study will collect clinical and laboratory data to elucidate immunotolerance and preventiv stategies with the aim to develop new and individual treatment options of atopic diseases.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Skin microbiome analysis of a junctional epidermolysis bullosa patient treated with genetically modified stem cells.
Dermietzel A, Tosun B, Nguyen M, Wessel K, et al · · 2025 · cited 1× · PMID 40509691 · DOI 10.1111/ddg.15776 -
Analyse des Hautmikrobioms eines an junktionaler Epidermolysis bullosa erkrankten Patienten nach Behandlung mit genetisch modifizierten Stammzellen
Dermietzel A, Tosun B, Nguyen M, Wessel K, et al · · 2025
Verify or expand the search:
- PubMed search for NCT04240522
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atopic Dermatitis
Currently open trials in the same condition.
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- NCT07488065 — A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis Participants · Phase 1 · recruiting
- NCT07467564 — The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatit · recruiting
- NCT07358156 — A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and E · Phase 1 · recruiting
Other University of Zurich trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04240522 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Zurich
- Last refreshed: 5 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04240522.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing