NCT04237519: SFL

The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home

Completed NA Last updated 18 August 2023

What this trial tests

NA trial testing SFL training in Cognitive Decline Prevention in Robust Older Adults in 120 participants. Completed in 1 August 2021.

Timeline

11 January 2019

Primary endpoint
1 July 2021

1 August 2021

Quick facts

Lead sponsor	University of Lausanne Hospitals
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	120
Start date	11 January 2019
Primary completion	1 July 2021
Estimated completion	1 August 2021
Sites	4 locations across Belgium, Canada, Switzerland

Drugs / interventions tested

• SFL training
• Active controlled training

Conditions studied

• Cognitive Decline Prevention in Robust Older Adults — all drugs for Cognitive Decline Prevention in Robust Older Adults →
• Cognitive Decline Prevention in Pre-frail Older Adults — all drugs for Cognitive Decline Prevention in Pre-frail Older Adults →
• Physical Decline Prevention in Robust Older Adults — all drugs for Physical Decline Prevention in Robust Older Adults →
• Physical Decline Prevention in Pre-frail Older Adults — all drugs for Physical Decline Prevention in Pre-frail Older Adults →

Sponsor

University of Lausanne Hospitals

Who can join

Adults 60 to 100, any sex, with Cognitive Decline Prevention in Robust Older Adults or Cognitive Decline Prevention in Pre-frail Older Adults. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline. Therefore, combining these activities into a home-based computerized training program may represent a powerful approach to foster independent life at home. The StayFitLonger study is a 6-month multi-site randomized controlled, double-blind trial, which tests the efficacy of a home-based computerized intervention that combines physical and cognitive exercises through virtual coaching to enhance motivation.

In Switzerland, Canada and Belgium, a total of 128 older participants will be recruited and randomly assigned to one of two physical and cognitive home-based interventions for 6 months: StayFitLonger or active control training. The StayFitLonger intervention provides physical and cognitive training exercises, feedback and instructions through a virtual coach to optimize motivation. It also offers social and psycho-educational contents. Monthly supervision (home-visits and phone calls) will be provided during this 6-month intervention. Outcomes will be measured at baseline, and after 6 months of training.

This study will demonstrate the feasibility, sustainability and efficacy of a home-based multi-domain intervention program allowing further development and possible commercialization of a scientifically validated training program to slow down cognitive and physical decline.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Pre-frail older adults show improved cognition with StayFitLonger computerized home-based training: a randomized controlled trial.
   Belleville S, Cuesta M, Bieler-Aeschlimann M, Giacomino K, et al · · 2023 · cited 18× · PMID 36266559 · DOI 10.1007/s11357-022-00674-5
2. Rationale and protocol of the StayFitLonger study: a multicentre trial to measure efficacy and adherence of a home-based computerised multidomain intervention in healthy older adults.
   Belleville S, Cuesta M, Bieler-Aeschlimann M, Giacomino K, et al · · 2020 · cited 7× · PMID 32859156 · DOI 10.1186/s12877-020-01709-2