NCT04234685

Determining the Effectiveness of a New Phototherapy Treatment for the Knee Osteoarthritis

Completed NA Last updated 20 March 2025

What this trial tests

NA trial testing High Intensity Physio Light Therapy (HIPL Therapy™) in Osteoarthritis, Knee in 20 participants. Completed in 19 March 2019.

Timeline

8 November 2018

Primary endpoint
21 December 2018

19 March 2019

Quick facts

Lead sponsor	Jordan Miller, PT, PhD
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	20
Start date	8 November 2018
Primary completion	21 December 2018
Estimated completion	19 March 2019
Sites	1 location across Canada

Drugs / interventions tested

• High Intensity Physio Light Therapy (HIPL Therapy™)
• Education
• Aerobic Exercise — full drug profile →
• Resistance Exercise
• Placebo Physio Light Therapy (HIPL Therapy™)

Conditions studied

• Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

Jordan Miller, PT, PhD

Who can join

18 and older, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Light therapy (phototherapy) has previously been shown to help reduce pain for people with musculoskeletal pain conditions, such as knee osteoarthritis (OA). A new phototherapy has been developed that allows for customizing the intensity of light based on patient characteristics, such as the patient size and skin type. This new phototherapy approach needs to be evaluated to determine its effects. This study has been planned to determine how effective the new phototherapy is, but first it needs to be determined whether the study plans are feasible. This study will determine the feasibility of the full study by pilot testing the methods for the full trial with a group of 20 people with knee osteoarthritis. Participants will be randomly assigned to either receive the new phototherapy approach or a placebo phototherapy twice/week for four weeks. Pain and function will be measured over the four week treatment period and 12-weeks follow-up.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Determining the feasibility of a trial to evaluate the effectiveness of phototherapy versus placebo at reducing pain during physical activity for people with knee osteoarthritis: a pilot randomized controlled trial.
   Vader K, Abebe AB, Chala MB, Varette K, et al · · 2020 · cited 2× · PMID 33292671 · DOI 10.1186/s40814-020-00729-4