NCT04234178 is a NA clinical trial of Epidural in Labor Pain, sponsored by Ataturk University.

Who is sponsoring NCT04234178?

NCT04234178 is sponsored by Ataturk University.

What drugs are being tested in NCT04234178?

Interventions in NCT04234178: Epidural, Intrathecal+Epidural.

What condition does NCT04234178 study?

NCT04234178 studies Labor Pain.

Is NCT04234178 still recruiting?

NCT04234178 is currently completed. Last updated 8 February 2022.

Last reviewed 2022-02-08 · How we verify

NCT04234178

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dural Puncture Epidural Versus Combined Spinal Epidural With Epidural Volume Extension in Labor Analgesia

Completed NA Last updated 8 February 2022

What this trial tests

NA trial testing Epidural in Labor Pain in 60 participants. Completed in 7 February 2021.

Timeline

1 February 2020

Primary endpoint
1 February 2021

7 February 2021

Quick facts

Lead sponsor	Ataturk University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	1 February 2020
Primary completion	1 February 2021
Estimated completion	7 February 2021
Sites	2 locations across Turkey (Türkiye)

Drugs / interventions tested

Epidural
Intrathecal+Epidural — full drug profile →

Conditions studied

Labor Pain — all drugs for Labor Pain →

Sponsor

Ataturk University

Who can join

Adults 18 to 45, female only, with Labor Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Labor is the process where the cervix is prepared to allow the baby to pass from the uterine cavity to the outside world. In the ordinary course, it ends with spontaneous or instrumental vaginal delivery or cesarean section. Traditionally, the first stage in which the cervix is passively dilated in response to uterine contractions consists of the second stage in which the mother passes the baby through the vagina and the third stage, the exit of the placenta. In the first stage of labor, pain is caused by uterine contractions and pressure on the cervix. Pain is transmitted through the T10-L2 spinal nerves and is felt in the abdominal wall, waist, hips, or thighs. In the second stage, pain from the vagina and perineum is added to uterine pain. This pain is transmitted by the pudendal nerves through the S2-4 nerve roots. In this study, we aimed to investigate the effects of dural puncture epidural analgesia versus combined spinal-epidural analgesia with epidural volume extension on labor variables.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Epidural volume extension versus dural puncture epidural analgesia for labor: A prospective randomized study.
Doymus O, Aydin ME, Bedir Z, Tor IH, et al · · 2025 · PMID 40068075 · DOI 10.1097/md.0000000000041691

Verify or expand the search:

Other trials of Epidural

Trials testing the same drug.

NCT06651762 — Ultra Sound Guided Genicular Nerves Cooled Radiofrequency Ablation in Total Knee Replacement Surgeries · NA · recruiting
NCT05993273 — Pain Control After VATS Anatomical Pulmonary Resections · NA · completed
NCT03700411 — Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer Surgery · Phase 4 · completed
NCT06386250 — Comparison of Regional Block, Caudal Block and Wound Infiltration in Inguinal Hernitomy · NA · completed
NCT03570996 — A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy · NA · terminated

Other recruiting trials for Labor Pain

Currently open trials in the same condition.

NCT07440069 — Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor · Phase 4 · recruiting
NCT07411352 — Left Lateral Position vs Supine Position to Reduce Active Labor Duration · NA · recruiting
NCT07401147 — Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Management During Labor. · NA · recruiting
NCT07395934 — Comparing PIEB and CEI for Labor Pain Relief · NA · recruiting
NCT06819579 — Exploring the Optimal Concentration of Lidocaine Test Dose for Labor Analgesia · NA · active not recruiting

Other Ataturk University trials

Trials by the same sponsor.

NCT07518537 — Bulk-Fill Composite Restorations: Clinical Evaluation · NA · not yet recruiting
NCT07241156 — Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression · NA · not yet recruiting
NCT07451418 — The Effect of Mindfulness Compassionate Living Training on Unwanted Pregnancies · NA · not yet recruiting
NCT07464548 — Effects of Stoma Education on Patients · NA · recruiting
NCT07375277 — Effects Of Biceps Transposition Without Tenotomy For Augmentation Of Massive Rotator Cuff Repairs · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04234178 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ataturk University
Last refreshed: 8 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04234178.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing