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NCT04232722: HCC
Sorafenib Combined With Arsenical in Treating Patients With Recurrent HCC After Liver Transplantation
Phase 2 trial testing Arsenicals in HCC in 43 participants. Status unknown.
31 December 2021
Quick facts
| Lead sponsor | Zhejiang University |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 43 |
| Start date | 1 January 2020 |
| Primary completion | 31 December 2021 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across China |
Drugs / interventions tested
- Arsenicals — full drug profile →
Conditions studied
- HCC — all drugs for HCC →
Sponsor
Zhejiang University
Who can join
Adults 18 to 75, any sex, with HCC. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To analyze the safety, efficacy and pharmacokinetic characteristics of sorafenib combined with compound huangdai tablets in patients with recurrent hepatocellular carcinoma after liver transplantation
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Glucose Metabolism and Oxidative Stress in Hepatocellular Carcinoma: Role and Possible Implications in Novel Therapeutic Strategies.
Mossenta M, Busato D, Dal Bo M, Toffoli G. · · 2020 · cited 60× · PMID 32585931 · DOI 10.3390/cancers12061668 -
Systemic Treatment for Hepatocellular Carcinoma Recurrence After Liver Transplantation.
Mazzarelli C, Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group, Berardi F, Bonfichi A, et al · · 2026 · PMID 41892169 · DOI 10.3390/curroncol33030141
Verify or expand the search:
- PubMed search for NCT04232722
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Zhejiang University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04232722 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhejiang University
- Last refreshed: 18 January 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04232722.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing