NCT04228107

Treatment Phenotypes for Adolescents With Asthma

Completed NA Results posted Last updated 6 November 2025

What this trial tests

NA trial testing Medication monitoring in Asthma in Children in 80 participants. Completed in 14 July 2024.

Timeline

16 November 2020

Primary endpoint
14 July 2024

14 July 2024

Quick facts

Lead sponsor	University of Colorado, Denver
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	health services research
Enrollment	80
Start date	16 November 2020
Primary completion	14 July 2024
Estimated completion	14 July 2024
Sites	1 location across United States

Drugs / interventions tested

• Medication monitoring

Conditions studied

• Asthma in Children — all drugs for Asthma in Children →
• Adherence, Treatment — all drugs for Adherence, Treatment →

Sponsor

University of Colorado, Denver

Who can join

Adults 12 to 90, any sex, with Asthma in Children or Adherence, Treatment. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Treatment Phenotypes Primary · 12 months

The Investigators will calculate the number of participants that fall into the following treatment phenotypes: "Well controlled-good adherence", "Well controlled-poor adherence", "Poorly controlled-good adherence", "Poorly controlled-poor adherence". We had initially planned to report only these 4 groups, however there was a very clear breakdown into 9 groups-as we needed to consider a moderately controlled group and a moderately adherent group. Therefore the groups are reported as follows: Poor Adhrence, Poor control Poor adherence, moderate control poor adherence, good control Moderate ad

Poor adherence, good control

Group	Value	95% CI
Adolescents	7

poor adherence, poor control

Group	Value	95% CI
Adolescents	2

Moderate adherence, good control

Group	Value	95% CI
Adolescents	10

moderate adherence, poor control

Group	Value	95% CI
Adolescents	5

high adherence, good control

Group	Value	95% CI
Adolescents	16

high adherence, poor control

Group	Value	95% CI
Adolescents	3

Qualitative Information Regarding Barriers for Medication Use Secondary · 12 months

Qualitative data (semistructured interviews with patients regarding barriers to medication use.

Theme: poor routine

Group	Value	95% CI
Adolescent Interviews	8

Theme: forget

Group	Value	95% CI
Adolescent Interviews	3

Qualitative Information Regarding Facilitators for Medication Use Secondary · 12 months

Qualitative data (semistructured interviews with adolescents) regarding barriers to medication use.

Theme: habit

Group	Value	95% CI
Adolescent Interviews	7

Theme: parental reminders

Group	Value	95% CI
Adolescent Interviews	8

Theme: good routine

Group	Value	95% CI
Adolescent Interviews	12

Qualitative Information Regarding Facilitators for Medication Use Secondary · 12 months

Qualitative data (focus groups with healthcare providers) to determine facilitators to medication use.

Theme: buy in from patient/family

Group	Value	95% CI
Provider Focus Groups	5

Theme: tailored approach

Group	Value	95% CI
Provider Focus Groups	7

Qualitative Information Regarding Barriers for Medication Use Secondary · 12 months

Qualitative data (focus groups with healthcare providers) to determine facilitators to medication use.

Theme: lack of parental involvement or parenting challenges

Group	Value	95% CI
Provider Focus Groups	5

Theme: insurance/cost barriers

Group	Value	95% CI
Provider Focus Groups	5

Theme: lack of adolescent understanding or prioritization

Group	Value	95% CI
Provider Focus Groups	7

Sponsor's own description

This study will evaluate how adolescents take their asthma medications using an electronic medication monitor.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.