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NCT04226716: PROFit
The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain
NA trial testing Assessment of postural control, body perception, psychosocial factors and inflammation in Pelvic Girdle Pain in 192 participants. Currently enrolling.
30 September 2027
Quick facts
| Lead sponsor | Hasselt University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 192 |
| Start date | 1 June 2020 |
| Primary completion | 30 September 2027 |
| Estimated completion | 30 September 2028 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Assessment of postural control, body perception, psychosocial factors and inflammation
Conditions studied
- Pelvic Girdle Pain — all drugs for Pelvic Girdle Pain →
- Low Back Pain — all drugs for Low Back Pain →
Sponsor
Hasselt University
Who can join
Adults 18 to 40, female only, with Pelvic Girdle Pain or Low Back Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A large proportion of pregnant women develop pregnancy-related low back and/or pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP are thus crucial. However, the underlying mechanisms of PPGP are still poorly understood. The main objective of this study is to investigate whether lumbar proprioceptive deficits, a disturbed body perception at the lumbar spine, psychosocial factors (incl. pain-related fear of movement, depression, anxiety and stress) and increased serum concentrations of specific inflammatory mediators are associated with (1) a reduced postural control and (2) the development and/or persistence of PPGP in multiparous women during the first and third trimester of pregnancy, and six weeks and six months postpartum.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04226716
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Assessment of postural control, body perception, psychosocial factors and inflammation
Trials testing the same drug.
- NCT06785909 — Proprioceptive, Fear-related and Inflammatory Factors in the Persistence of Pregnancy-related Lumbopelvic Pain. · NA · recruiting
Other recruiting trials for Pelvic Girdle Pain
Currently open trials in the same condition.
- NCT07037368 — Impact of Delivery Mode on Coccydynia, Pelvic Girdle Pain and Rectus Diastasis in Postpartum Females · active not recruiting
- NCT06785909 — Proprioceptive, Fear-related and Inflammatory Factors in the Persistence of Pregnancy-related Lumbopelvic Pain. · NA · recruiting
- NCT07158957 — WOMENinMOTION An Intervention Model for Pelvic Girdle Pain · NA · recruiting
- NCT06284278 — Telehealth: Diaphragmatic vs. Pelvic Exercise in Postpartum Pregnancy-related Pelvic Girdle Pain · NA · recruiting
- NCT05507853 — Exploring Central Sensitization in Pregnant Women · recruiting
Other Hasselt University trials
Trials by the same sponsor.
- NCT07419100 — Sedentary Behaviour, Physical Activity Patterns, and Cardiometabolic Health · NA · not yet recruiting
- NCT07505355 — Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis · recruiting
- NCT07081893 — How do Patients, Relatives and Healthcare Professionals View Person-centered Rehabilitation. · not yet recruiting
- NCT06785909 — Proprioceptive, Fear-related and Inflammatory Factors in the Persistence of Pregnancy-related Lumbopelvic Pain. · NA · recruiting
- NCT07175792 — Accuracy of Motor Performance Perception in Multiple Sclerosis · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04226716 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hasselt University
- Last refreshed: 3 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04226716.
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