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NCT04223817: PREM'S
7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis
NA trial testing 7.0 T RMI in Systemic Sclerosis (SSc) in 50 participants. Completed in 2 September 2025.
2 September 2025
Quick facts
| Lead sponsor | Poitiers University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 50 |
| Start date | 12 April 2021 |
| Primary completion | 2 September 2025 |
| Estimated completion | 2 September 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- 7.0 T RMI
Conditions studied
- Systemic Sclerosis (SSc) — all drugs for Systemic Sclerosis (SSc) →
- Magnetic Resonance Imaging (MRI) — all drugs for Magnetic Resonance Imaging (MRI) →
Sponsor
Poitiers University Hospital
Who can join
18 and older, any sex, with Systemic Sclerosis (SSc) or Magnetic Resonance Imaging (MRI). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Systemic sclerosis (SSc) is a rare systemic autoimmune disease with specific osteoarticular pattern of unknown mechanism. Ischemic phenomenon have been suggested to participate to the osteoarticular involvement in SSc. To date, osteoarticular pattern and hand vascular involvement have been few studied in magnetic resonance imaging in SSc, and most often with low resolution RMI. 7 Tesla RMI allows high resolution for morphology examination, together with dynamic and functional vascular study and sodium articular concentration. Indeed, the aim of the study is to describe hand osteoarticular and vascular involvement in SSc, as well as sodium articular concentration. Clinico-biological association will be also assessed.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04223817
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Poitiers University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04223817 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Poitiers University Hospital
- Last refreshed: 29 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04223817.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing