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NCT04217980: PROLUSP
Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
NA trial testing Lung ultrasonography (LUS) or Chest X ray (CXR) in Pneumonia Childhood in 202 participants. Completed in 3 December 2019.
9 September 2019
Quick facts
| Lead sponsor | Fundació Sant Joan de Déu |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | diagnostic |
| Enrollment | 202 |
| Start date | 21 September 2017 |
| Primary completion | 9 September 2019 |
| Estimated completion | 3 December 2019 |
| Sites | 2 locations across Spain |
Drugs / interventions tested
- Lung ultrasonography (LUS) or Chest X ray (CXR)
Conditions studied
- Pneumonia Childhood — all drugs for Pneumonia Childhood →
Sponsor
Fundació Sant Joan de Déu — full company profile →
Who can join
Adults 7 Days to 18, any sex, with Pneumonia Childhood. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lung ultrasound (LUS) in combination with a biomarker has not yet been studied. The investigators propose a clinical trial where the primary aims are: 1. To assess whether an algorithm with LUS and procalcitonin (PCT) may be useful for diagnosing bacterial pneumonia; 2. To analyse the sensitivity and specificity of LUS vs chest radiograph (CXR).
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
A training plan to implement lung ultrasound for diagnosing pneumonia in children.
Guitart C, Esteban E, Becerra J, Rodríguez-Fanjul J, et al · · 2022 · cited 10× · PMID 34969992 · DOI 10.1038/s41390-021-01928-2 -
Procalcitonin and lung ultrasound algorithm to diagnose severe pneumonia in critical paediatric patients (PROLUSP study). A randomised clinical trial.
Rodríguez-Fanjul J, Guitart C, Bobillo-Perez S, Balaguer M, et al · · 2020 · cited 7× · PMID 33032612 · DOI 10.1186/s12931-020-01476-z -
Lung ultrasound and procalcitonin, improving antibiotic management and avoiding radiation exposure in pediatric critical patients with bacterial pneumonia: a randomized clinical trial.
Guitart C, Bobillo-Perez S, Rodríguez-Fanjul J, Carrasco JL, et al · · 2024 · cited 6× · PMID 38581075 · DOI 10.1186/s40001-024-01712-y
Verify or expand the search:
- PubMed search for NCT04217980
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pneumonia Childhood
Currently open trials in the same condition.
- NCT07414693 — Effect of Vitamin C on Length of Hospital Stay in Children With Severe Pneumonia · Phase 4 · recruiting
- NCT06921993 — Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia · NA · recruiting
Other Fundació Sant Joan de Déu trials
Trials by the same sponsor.
- NCT07508917 — Effects of 5-Methyltetrahydrofolic Acid Supplementation on Maternal Health and One-Carbon Metabolism During Lactation · Phase 1, PHASE2 · not yet recruiting
- NCT06556251 — Effectiveness of a Digital Platform in Engagement and Prognosis of Patients in an Early Intervention Pychosis Programme · NA · recruiting
- NCT06309121 — Effects of the Postbiotic Blend ABB C3 on Adiposity and Glucose Metabolism in Children and Adolescents · NA · active not recruiting
- NCT07091344 — Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis · NA · recruiting
- NCT06340555 — Intervention to Prevent Mental Health Disorders of Women and Their Partners Who Experienced Pregnancy Loss · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04217980 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundació Sant Joan de Déu
- Last refreshed: 13 January 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04217980.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing