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NCT04217226
Perfusion Index-derived Parameters as Predictors Post-induction Hypotension.
trial testing Perfusion index derived parameters in Hypotension in 93 participants. Completed in 28 July 2020.
5 June 2020
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 93 |
| Start date | 20 January 2020 |
| Primary completion | 5 June 2020 |
| Estimated completion | 28 July 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Perfusion index derived parameters
Conditions studied
- Hypotension — all drugs for Hypotension →
- General Anesthesia Induced Hypotension — all drugs for General Anesthesia Induced Hypotension →
Sponsor
Cairo University
Who can join
Adults 18 to 59, any sex, with Hypotension or General Anesthesia Induced Hypotension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The perfusion index (PI) is a numerical value for the ratio between pulsatile and non-pulsatile blood flow measured by a special pulse oximeter. PI represents the baseline sympathetic tone which is assumed one of the factors contributing for hypotension. Patients with low PI were reported by Mahendale and Rajasekhar to show greater hypotension after induction of anesthesia. This was explained by the high sympathetic tone in these patients which is suddenly masked by propofol administration leading to profound hypotension. This study aims to evaluate the ability of preoperative plethysmographic variability index, perfusion index and the Dicrotic Plethysmography to predict post-induction hypotension.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Perfusion index-derived parameters as predictors of hypotension after induction of general anaesthesia: a prospective cohort study.
Abdelhamid B, Yassin A, Ahmed A, Amin S, et al · · 2022 · cited 6× · PMID 35359139 · DOI 10.5114/ait.2022.113956
Verify or expand the search:
- PubMed search for NCT04217226
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04217226 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 30 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04217226.
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