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NCT04217018

MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence

Recruiting now Last updated 8 February 2021
What this trial tests

trial testing Prediction of molecular pathology in Glioma in 3,000 participants. Currently enrolling.

Timeline
1 January 2017
Primary endpoint
1 January 2027
1 June 2027

Quick facts

Lead sponsorThe First Affiliated Hospital of Zhengzhou University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment3,000
Start date1 January 2017
Primary completion1 January 2027
Estimated completion1 June 2027
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

The First Affiliated Hospital of Zhengzhou University

Who can join

Adults 1 to 95, any sex, with Glioma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This registry aims to collect clinical, molecular and radiologic data including detailed clinical parameters, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and conventional/advanced/new MR sequences (T1, T1c, T2, FLAIR, ADC, DTI, PWI, etc) of patients with primary gliomas. By leveraging artificial intelligence, this registry will seek to construct and refine algorithms that able to predict molecular pathology or subgroups of gliomas.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Artificial Intelligence in Neurosurgery: A State-of-the-Art Review from Past to Future.
    Tangsrivimol JA, Schonfeld E, Zhang M, Veeravagu A, et al · · 2023 · cited 43× · PMID 37510174 · DOI 10.3390/diagnostics13142429
  2. Radiomic features from multiparametric magnetic resonance imaging predict molecular subgroups of pediatric low-grade gliomas.
    Liu Z, Hong X, Wang L, Ma Z, et al · · 2023 · cited 10× · PMID 37697238 · DOI 10.1186/s12885-023-11338-8

Verify or expand the search:

Other recruiting trials for Glioma

Currently open trials in the same condition.

Other The First Affiliated Hospital of Zhengzhou University trials

Trials by the same sponsor.

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Data sources for this page

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