NCT04216147 is a NA clinical trial of PNE in Carpal Tunnel Syndrome, sponsored by Universidad de Murcia.

Who is sponsoring NCT04216147?

NCT04216147 is sponsored by Universidad de Murcia.

What drugs are being tested in NCT04216147?

Interventions in NCT04216147: PNE, Surgery for CTS.

What condition does NCT04216147 study?

NCT04216147 studies Carpal Tunnel Syndrome.

Is NCT04216147 still recruiting?

NCT04216147 is currently completed. Last updated 2 January 2020.

Last reviewed 2020-01-02 · How we verify

NCT04216147

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Percutaneous Needle Electrolysis Versus Surgery in the Treatment of Carpal Tunnel Syndrome

Completed NA Last updated 2 January 2020

What this trial tests

NA trial testing PNE in Carpal Tunnel Syndrome in 140 participants. Completed in 31 January 2019.

Timeline

1 December 2015

Primary endpoint
1 January 2019

31 January 2019

Quick facts

Lead sponsor	Universidad de Murcia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	140
Start date	1 December 2015
Primary completion	1 January 2019
Estimated completion	31 January 2019

Drugs / interventions tested

PNE
Surgery for CTS

Conditions studied

Carpal Tunnel Syndrome — all drugs for Carpal Tunnel Syndrome →

Sponsor

Universidad de Murcia — full company profile →

Who can join

18 and older, any sex, with Carpal Tunnel Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to compare the effectiveness of Percutaneous Needle Electrolysis (PNE) versus surgical treatment in the treatment of Carpal Tunnel Syndrome (CTS).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Surgical versus non-surgical treatment for carpal tunnel syndrome.
Lusa V, Karjalainen TV, Pääkkönen M, Rajamäki TJ, et al · · 2024 · cited 9× · PMID 38189479 · DOI 10.1002/14651858.cd001552.pub3
Ultrasound Characteristics of Carpal Tunnel Syndrome in the Spanish Population.
García-Bermejo P, Segura-León J, Medina-I-Mirapeix F, Valera-Garrido F. · · 2025 · cited 1× · PMID 39921397 · DOI 10.1002/jcu.23911
Ultrasound-Guided Percutaneous Needle Electrolysis Versus Surgery for Carpal Tunnel Syndrome: A Randomized Clinical Trial
Valera-Garrido F, Segura-León J, García-Bermejo P, Medina-Mirapeix F. · · 2026

Verify or expand the search:

Other trials of PNE

Trials testing the same drug.

NCT06739694 — Neuroscience Education in Shoulder Pain: Clinical Trial · NA · completed
NCT04042012 — Percutaneous Needle Electrolysis (PNE) in Soleus Injury · NA · completed
NCT03523949 — Pain Neuroscience Education in Old Adults. · NA · unknown

Other recruiting trials for Carpal Tunnel Syndrome

Currently open trials in the same condition.

NCT07312123 — A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome · NA · recruiting
NCT07334964 — Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method · NA · recruiting
NCT07414069 — High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological Outcomes · NA · recruiting
NCT07114913 — Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome · recruiting
NCT06905769 — Effects of Aquatic Therapy Versus Neuro-dynamic Technique for the Treatment of Carpal Tunnel Syndrome Patient · NA · active not recruiting

Other Universidad de Murcia trials

Trials by the same sponsor.

NCT07310459 — Perinatal Risk Factors in Motor Development · not yet recruiting
NCT06982456 — Manual Therapy Techniques for Cervical Pain: Algometric Evaluation · NA · enrolling by invitation
NCT06910150 — Effectiveness of a Session of Analgesic Electrostimulation (Invasive and Non-invasive) Applied to the Quadriceps Muscle · NA · enrolling by invitation
NCT06206499 — Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant · NA · unknown
NCT06240416 — Autogenous Particles Harvesting During Implant Surgery · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04216147 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad de Murcia
Last refreshed: 2 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04216147.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing