Last reviewed · How we verify
NCT04212481
RCT of Uniport VATS for Lung Cancer
NA trial testing uniport video-assisted thoracoscopic surgery in Single-port Video-assisted Thoracoscopic Surgery in 300 participants. Status unknown.
30 December 2022
Quick facts
| Lead sponsor | The Second Hospital of Shandong University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 25 December 2019 |
| Primary completion | 30 December 2022 |
| Estimated completion | 30 December 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- uniport video-assisted thoracoscopic surgery
- two ports video-assisted thoracoscopic surgery
- three ports video-assisted thoracoscopic surgery
Conditions studied
- Single-port Video-assisted Thoracoscopic Surgery — all drugs for Single-port Video-assisted Thoracoscopic Surgery →
Sponsor
The Second Hospital of Shandong University
Who can join
Adults 25 to 80, any sex, with Single-port Video-assisted Thoracoscopic Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Video-assisted thoracoscopic surgery (VATS) has been widely used for non-small cell lung cancer (NSCLC) for nearly two decades. Usually, it was applied through three ports with at least one drainage after surgery, which often lead to acute chest pain. Therefore, fewer, smaller ports, and wider intercostal space for surgery has been required. Uniport VATS became a feasible option with the development of surgical techniques and instruments, with potentially less postoperative pain and shorter hospital stays. However, there may be some complications, or with a longer time of operation, even more difficult in lymph nodes resection during learning curve. In our study, a Randomized Controlled Trial was designed to study the operation time, perioperative blood loss, conversion rate, duration of postoperative drainage, length of hospital stay, visual analogue score of postoperative pain, complications, and survival.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Randomized controlled trials in lung cancer surgery: How are we doing?
Wong LY, Li Y, Elliott IA, Backhus LM, et al · · 2024 · cited 1× · PMID 38690441 · DOI 10.1016/j.xjon.2024.01.008
Verify or expand the search:
- PubMed search for NCT04212481
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04212481 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Second Hospital of Shandong University
- Last refreshed: 16 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04212481.
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