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NCT04211077: SANTE

Suicidal Risk Factors Associated With Opioid Analgesics Use

Completed Last updated 2 September 2021
What this trial tests

trial testing Date collection in SNIIRAM Database in 273,221 participants. Completed in 1 June 2021.

Timeline
1 January 2020
Primary endpoint
1 December 2020
1 June 2021

Quick facts

Lead sponsorUniversity Hospital, Montpellier
StatusCompleted
Study typeOBSERVATIONAL
Enrollment273,221
Start date1 January 2020
Primary completion1 December 2020
Estimated completion1 June 2021
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Montpellier

Who can join

18 and older, any sex, with SNIIRAM Database. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is an increase in prescriptions for analgesics opioids and overdose mortality in France. In the United States, the consumption of opioid analgesics is associated with excess mortality, especially suicide. In France, the investigator team showed retrospectively a link between history of suicide attempt (SA) and use of analgesics in general elderly population. It is important to determine if there is a link between the prescription of opioid analgesics and suicide attempts, in a longitudinal study in general population. The originality of the project lies in: * the absence of a French epidemiological study on the link between opioid analgesics and suicide attempt / mortality despite the context of "opioid crisis", * taking into account the terms of consumption of care

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Association Between Opioid Analgesics and Suicide Attempts: A Nationwide French Case-Crossover Study.
    Nobile B, Nogue E, Picot MC, Courtet P, et al · · 2025 · PMID 40884605 · DOI 10.1007/s40263-025-01221-4

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Other trials of Date collection

Trials testing the same drug.

Other University Hospital, Montpellier trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04211077.

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