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NCT04209881

Ovarian Reserve and Ankylosing Spondylitis

Completed Last updated 22 May 2020
What this trial tests

trial testing ovarian reserve for Ankylosing spondylitis and control groups in Ovarian Diseases in 50 participants. Completed in 19 May 2020.

Timeline
19 December 2019
Primary endpoint
19 May 2020
19 May 2020

Quick facts

Lead sponsorKanuni Sultan Suleyman Training and Research Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment50
Start date19 December 2019
Primary completion19 May 2020
Estimated completion19 May 2020
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Who can join

Adults 18 to 45, female only, with Ovarian Diseases or Ankylosing Spondylitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study was to determine the status of ovarian reserve in patients with ankylosing spondylitis (AS) using anti-mullerian hormone (AMH) level and antral follicle count (AFC). Women with AS and women controls diagnosed according to the classification criteria proposed by the American-European Consensus Group will be included in the study. Ovarian reserve will be evaluated in terms of clinical findings, AFC and serum AMH and reproductive hormone levels. Researchers predict that the ovarian reserve may be reduced in patients with AS due to the autoimmune process and the pathophysiology of the disease. Serum AMH and ovarian AFC may be useful for assessing ovarian reserve. It is aimed to determine the course of ovarian reserve abnormalities and the best possible biomarkers of reduced ovarian reserve in patients with AS.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Ovarian reserve in patients with ankylosing spondylitis.
    Yalçın Bahat P, Kadiroğulları P, Topbas Selcuki NF, Yücel B, et al · · 2021 · cited 8× · PMID 33030584 · DOI 10.1007/s00404-020-05824-8

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Data sources for this page

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