NCT04206306 is a clinical trial in Adult Patients, sponsored by National Taiwan University Hospital.

Who is sponsoring NCT04206306?

NCT04206306 is sponsored by National Taiwan University Hospital.

What condition does NCT04206306 study?

NCT04206306 studies Adult Patients, Intensive Care Unit.

Is NCT04206306 still recruiting?

NCT04206306 is currently completed. Last updated 20 January 2025.

Last reviewed 2025-01-20 · How we verify

NCT04206306

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Functional Recovery Over the First Year After ICU Discharge

Completed Last updated 20 January 2025

What this trial tests

trial in Adult Patients in 407 participants. Completed in 12 July 2021.

Timeline

14 August 2018

Primary endpoint
26 November 2020

12 July 2021

Quick facts

Lead sponsor	National Taiwan University Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	407
Start date	14 August 2018
Primary completion	26 November 2020
Estimated completion	12 July 2021
Sites	1 location across Taiwan

Conditions studied

Adult Patients — all drugs for Adult Patients →
Intensive Care Unit — all drugs for Intensive Care Unit →

Sponsor

National Taiwan University Hospital

Who can join

20 and older, any sex, with Adult Patients or Intensive Care Unit. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intensive Care Unit Acquired Delirium (ICU-AD) and Intensive Care Unit Acquired Weakness (ICU-AW) are common in critically ill, mechanically ventilated adult patients. As more patients survive ICU stays but suffer from long-term functional declines leading to unemployment and disability, research is urgently needed. The aims of this study are to: 1) describe the trajectory of physical functions one year after ICU discharge, including distance walked in 6 minutes (6MWD), hand grip (HGS), maximum inspiratory pressure (MIP), cognitive function (mini mental state examination,MMSE), physical function ICU test score (PFITs) , medical reserach council scale (MRC), medical research council questionnaire (MRC-Q)and basic and instrumental activities of daily living (ADL/IADL); 2) examine the incidences of ICU-AD and ICU-AW; and 3) test the interaction between ICU-AD and ICU-AW on one-year functional trajectories in the ICU survivors.4) compare two tools, the intensive care delirium screening checklist (ICDSC) and confusion assessment method for the ICU (CAM-ICU), for their predictive validity for outcomes related to delirium, hospital mortality and length of stay (LOS), and examined whether the tools' predictive validity was affected by patients' arousal status (RASS≥0, RASS\<0).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Delirium and Weakness Acquired in the Intensive Care Unit: Individual and Combined Effects on 90-Day Mortality in Survivors of Critical Illness.
Siao SF, Zheng YY, Wei YC, Boehm LM, et al · · 2025 · cited 1× · PMID 39468861 · DOI 10.1111/jocn.17517
ICU Delirium Patterns and 30-Day Mortality in Critically Ill Adults.
Siao SF, Ku SC, Hsu AS, Wei YC, et al · · 2026 · PMID 42132087 · DOI 10.1111/nicc.70514

Verify or expand the search:

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Other National Taiwan University Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04206306 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 20 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04206306.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing