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NCT04204356
The Effect of Non-invasive Brain Stimulation on Language Production in Post-stroke Aphasia
NA trial testing Language treatment for improving discourse production in Aphasia in 6 participants. Completed in 5 November 2020.
28 August 2020
Quick facts
| Lead sponsor | King's College London |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 6 |
| Start date | 25 November 2019 |
| Primary completion | 28 August 2020 |
| Estimated completion | 5 November 2020 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Language treatment for improving discourse production
- Transcranial direct-current stimulation (tDCS)
Conditions studied
- Aphasia — all drugs for Aphasia →
- Stroke — all drugs for Stroke →
- Language Disorders — all drugs for Language Disorders →
Sponsor
King's College London
Who can join
18 and older, any sex, with Aphasia or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aphasia is a language impairment caused by brain injury such as stroke that affects the ability to understand and express language, read and write due to damage in the language regions of the brain. Non-invasive brain stimulation (NIBS) techniques like transcranial direct-current stimulation (tDCS) have been found to improve aphasia treatment effects in post stroke patient populations such as improved naming abilities. However, the effect of tDCS on more functional, higher level language skills such as discourse production (i.e. story telling, giving instructions) has yet to be understood.Therefore the aim of this study is to determine the potential effectiveness of tDCS as an adjunct to speech and language therapy (SLT) to improve discourse speech production in people with post-stroke aphasia. It is hypothesised that SLT combined with tDCS will result in greater improvements in discourse language production compared to SLT on its own.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04204356
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Aphasia
Currently open trials in the same condition.
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- NCT07397923 — Exploratory Evaluation of the Digital Therapeutic Device Zenicom for Subacute Stroke Aphasia · Phase 2 · recruiting
- NCT07281313 — Aphasia Physical EXercise Study: Randomized Trial · NA · recruiting
- NCT06990997 — Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia · NA · recruiting
- NCT06974279 — Post-Stroke Aphasia TMS · NA · recruiting
Other King's College London trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04204356 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King's College London
- Last refreshed: 18 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04204356.
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