Last reviewed · How we verify
NCT04203212
BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH
trial testing Goserelin Acetate in Endometriosis in 41 participants. Completed in 31 December 2020.
1 December 2020
Quick facts
| Lead sponsor | 424 General Military Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 41 |
| Start date | 1 October 2019 |
| Primary completion | 1 December 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Goserelin Acetate (GOSERELIN ACETATE) — full drug profile →
Conditions studied
- Endometriosis — all drugs for Endometriosis →
- Bone Density — all drugs for Bone Density →
- Muscle — all drugs for Muscle →
- Bone Metabolism — all drugs for Bone Metabolism →
Sponsor
424 General Military Hospital
Who can join
Adults 18 to 45, female only, with Endometriosis or Bone Density. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aim to investigate the effect of menstrual cessation in women with endometriosis treated with GnRH analogs for 6 months on bone mineral density and bone and muscle metabolism parameters and subsequently the effects of menstrual restoration after GnRH analogs discontinuation on the above measured parameters
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Lipid Profile after Pharmacologic Discontinuation and Restoration of Menstruation in Women with Endometriosis: A 12-Month Observational Prospective Study.
Anastasilakis AD, Polyzos SA, Vorkas PA, Gkiomisi A, et al · · 2023 · cited 6× · PMID 37629472 · DOI 10.3390/jcm12165430
Verify or expand the search:
- PubMed search for NCT04203212
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Goserelin Acetate
Trials testing the same drug.
- NCT07460752 — Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally A · Phase 2 · not yet recruiting
- NCT04734730 — Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer · Phase 2 · recruiting
- NCT04484818 — Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With · Phase 3 · active not recruiting
- NCT04423211 — Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging · Phase 3 · recruiting
- NCT03678025 — Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer · Phase 3 · recruiting
Other recruiting trials for Endometriosis
Currently open trials in the same condition.
- NCT06559852 — The Impact of Yoga on Endometriosis-Related Pain · NA · recruiting
- NCT07393295 — Efficacy and Tolerability of TENS in Endometriosis-related Pain · NA · recruiting
- NCT07134023 — Educational Program for the Multidisciplinary Support of Patients With Endometriosis · NA · recruiting
- NCT07240883 — ENDO1000 - A UK-wide Endometriosis Research Project · recruiting
- NCT06974773 — Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups · NA · recruiting
Other 424 General Military Hospital trials
Trials by the same sponsor.
- NCT04766151 — Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial) · Phase 3 · unknown
- NCT04206618 — Circulating Myokine Levels and Bone Metabolism · completed
- NCT03098667 — Laryngeal Mask Airway (LMA) Protector for Minimally Invasive Thyroidectomy · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04203212 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by 424 General Military Hospital
- Last refreshed: 12 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04203212.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing