NCT04200560 is a NA clinical trial of Rhythmic Handgrip Exercise in Vascular Diseases, sponsored by University of Utah.

Who is sponsoring NCT04200560?

NCT04200560 is sponsored by University of Utah.

What drugs are being tested in NCT04200560?

Interventions in NCT04200560: Rhythmic Handgrip Exercise, Chronic Exercise Training.

What condition does NCT04200560 study?

NCT04200560 studies Vascular Diseases.

Is NCT04200560 still recruiting?

NCT04200560 is currently completed. Last updated 22 August 2022.

Last reviewed 2022-08-22 · How we verify

NCT04200560

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS

Completed NA Last updated 22 August 2022

What this trial tests

NA trial testing Rhythmic Handgrip Exercise in Vascular Diseases in 16 participants. Completed in 30 May 2022.

Timeline

1 July 2018

Primary endpoint
30 May 2022

30 May 2022

Quick facts

Lead sponsor	University of Utah
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	16
Start date	1 July 2018
Primary completion	30 May 2022
Estimated completion	30 May 2022
Sites	1 location across United States

Drugs / interventions tested

Rhythmic Handgrip Exercise
Chronic Exercise Training

Conditions studied

Vascular Diseases — all drugs for Vascular Diseases →

Sponsor

University of Utah

Who can join

Adults 18 to 90, any sex, with Vascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Aging is inevitable and is the primary risk factor for developing cardiovascular disease. The molecular mechanisms that drive vascular dysfunction in the context of aging are incompletely understood. The overall hypothesis is that the age-related decline in endothelial cell (EC) autophagy leads to arterial dysfunction. This study will determine whether physiological shear-stress affects autophagosome formation and nitrous oxide (NO) generation in ECs.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The role of autophagy in cardiovascular pathology.
Gatica D, Chiong M, Lavandero S, Klionsky DJ. · · 2022 · cited 72× · PMID 33956077 · DOI 10.1093/cvr/cvab158

Verify or expand the search:

Other recruiting trials for Vascular Diseases

Currently open trials in the same condition.

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Other University of Utah trials

Trials by the same sponsor.

NCT07515755 — Supplemental Oxygen and Oxygen Desaturations in Colonoscopies · NA · not yet recruiting
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NCT06716411 — Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness · NA · recruiting
NCT07246538 — Positive Airway Pressure (PAP) System Evaluation in Volunteers · NA · not yet recruiting
NCT04208984 — Diversion Device With Breath Control · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04200560 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Utah
Last refreshed: 22 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04200560.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing