Who is sponsoring NCT04196335?

NCT04196335 is sponsored by Boston Scientific Corporation.

What drugs are being tested in NCT04196335?

Interventions in NCT04196335: intra-procedural intracardiac echocardiography.

What condition does NCT04196335 study?

NCT04196335 studies Efficacy, Self, Safety Issues.

Is NCT04196335 still recruiting?

NCT04196335 is currently completed. Last updated 18 June 2025.

Last reviewed 2025-06-18 · How we verify

NCT04196335: ICELAA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

I Can sEe Left Atrial Appendage (ICELAA) Clinical Study

Completed NA Last updated 18 June 2025

What this trial tests

NA trial testing intra-procedural intracardiac echocardiography in Efficacy, Self in 100 participants. Completed in 24 September 2021.

Timeline

29 July 2020

Primary endpoint
24 September 2021

24 September 2021

Quick facts

Lead sponsor	Boston Scientific Corporation
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	29 July 2020
Primary completion	24 September 2021
Estimated completion	24 September 2021
Sites	7 locations across Denmark, United Kingdom, Spain, Italy

Drugs / interventions tested

intra-procedural intracardiac echocardiography

Conditions studied

Efficacy, Self — all drugs for Efficacy, Self →
Safety Issues — all drugs for Safety Issues →

Sponsor

Boston Scientific Corporation — full company profile →

Who can join

18 and older, any sex, with Efficacy, Self or Safety Issues. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this study is to assess the efficacy and safety of using intra-procedural intracardiac echocardiography (ICE) for WATCHMAN FLX Device implants in subjects with non-valvular atrial fibrillation to reduce the risk of stroke.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Intracardiac Echocardiography to Guide Watchman FLX Implantation: The ICE LAA Study.
Nielsen-Kudsk JE, Berti S, Caprioglio F, Ronco F, et al · · 2023 · cited 50× · PMID 36764917 · DOI 10.1016/j.jcin.2022.10.024
Intracardiac echocardiography is a promising strategy for guiding closure of the left atrial appendage.
Ding X, Xiang K, Qian C, Hou X, et al · · 2023 · cited 1× · PMID 38116174 · DOI 10.1002/hsr2.1762
Anesthetic Choice for Percutaneous Transcatheter Closure of the Left Atrial Appendage: A National Anesthesia Clinical Outcomes Registry Analysis.
Hickman W, Dada RS, Thibault D, Gibson C, et al · · 2024 · PMID 38963356 · DOI 10.4103/aca.aca_14_24

Verify or expand the search:

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Other Boston Scientific Corporation trials

Trials by the same sponsor.

NCT07458243 — Registry of ENROUTE NPS in Conjunction With Carotid WALLSTENT · not yet recruiting
NCT07458217 — Combined CM and STN Stimulation for Motor Epilepsy · NA · not yet recruiting
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NCT07353710 — A Study on the Acquisition of 2D ICE Images With the CHORUS IDx System in Subjects Undergoing an Ablation Procedure · NA · not yet recruiting
NCT07195708 — Orbera365 Intragastric Balloon System (Abbreviated as'Orbera365') · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04196335 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Boston Scientific Corporation
Last refreshed: 18 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04196335.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing