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NCT04194398
OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection
trial testing OCS Lung System in OCS Lung System in 79 participants. Completed in 30 September 2021.
30 September 2021
Quick facts
| Lead sponsor | TransMedics |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 79 |
| Start date | 31 December 2018 |
| Primary completion | 30 September 2021 |
| Estimated completion | 30 September 2021 |
| Sites | 8 locations across Belgium, United States, Germany |
Drugs / interventions tested
- OCS Lung System
Conditions studied
- OCS Lung System — all drugs for OCS Lung System →
Sponsor
TransMedics — full company profile →
Who can join
18 and older, any sex, with OCS Lung System. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Collection of five year follow-up data on patients who have already participated in the EXPAND Lung trial and have had transplants with donor lungs preserved on the OCS Lung System.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Long-term outcomes of the international EXPAND trial of Organ Care System (OCS) Lung preservation for lung transplantation.
Loor G, Warnecke G, Villavicencio MA, Smith MA, et al · · 2025 · cited 5× · PMID 40686680 · DOI 10.1016/j.eclinm.2025.103334
Verify or expand the search:
- PubMed search for NCT04194398
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of OCS Lung System
Trials testing the same drug.
- NCT03868904 — INSPIRE Continuation Post-Approval Study · completed
- NCT03639025 — OCS™ Lung TOP Registry For Donor Lungs for Transplantation · active not recruiting
Other TransMedics trials
Trials by the same sponsor.
- NCT05915299 — US National OCS Heart Perfusion (OHP) Registry · recruiting
- NCT04615182 — Donor After Circulatory Death Heart CAP Trial · NA · completed
- NCT04194437 — OCS Liver DCD Trial · NA · terminated
- NCT04186221 — OCS Liver PROTECT Continued Access Protocol · NA · completed
- NCT05096754 — OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04194398 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by TransMedics
- Last refreshed: 7 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04194398.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing