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NCT04194333: CBCTENB
Cone Beam CT Guided Electromagnetic Navigational Bronchoscopy
trial testing Cone Beam CT with Embo Guide to creat 3D Overlay and CT Augmented Fluoroscopy to guide Electromagnetic Navigational Bronchoscopy instead of Standard Fluroscopic guidance using the C-Arm in Lung Nodule in 180 participants. Completed in 2 November 2021.
2 November 2021
Quick facts
| Lead sponsor | Columbus Regional Health |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 1 August 2017 |
| Primary completion | 2 November 2021 |
| Estimated completion | 2 November 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cone Beam CT with Embo Guide to creat 3D Overlay and CT Augmented Fluoroscopy to guide Electromagnetic Navigational Bronchoscopy instead of Standard Fluroscopic guidance using the C-Arm
Conditions studied
- Lung Nodule — all drugs for Lung Nodule →
- Lung Mass — all drugs for Lung Mass →
- Lesion of the Lung — all drugs for Lesion of the Lung →
Sponsor
Columbus Regional Health
Who can join
18 and older, any sex, with Lung Nodule or Lung Mass. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Electromagnetic navigation bronchoscopy (ENB) is used to access peripheral and central parenchymal lung lesions via endobronchial and transbronchial approach. Traditionally ENB is done under fluoroscopic guidance using C-arm but with development of Cone Beam CT and 3D reconstruction technology, fluoroscopy can be enhanced to much higher resolution and can also provide real time 3D augmentation of the lesion. It also enables the user to obtain a CT of the Chest to confirm the real time location of the lesion and the bronchoscopic biopsy catheter and instruments. This is thought to improve the yield and sensitivity of ENB guided Biopsy of the lung nodules and masses but has not been proven in a prospective trial. With my study, I want to examine the effect of Cone Beam CT with 3D reconstruction on the diagnostic yield and sensitivity of Electromagnetic Navigational Bronchoscopic biopsy of the lung lesions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04194333
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT06838806 — Epigenetic Nucleosomes in Plasma for Pulmonary Nodule Differentiation · recruiting
- NCT06054854 — Biobank for the Identification of Biomarkers in Lung Cancer (BIRD, Biomarkers in Respiratory Disease) · recruiting
Other Columbus Regional Health trials
Trials by the same sponsor.
- NCT05358041 — Cone Beam CT Guided Robotic Navigational Bronchoscopy · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04194333 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Columbus Regional Health
- Last refreshed: 21 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04194333.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing