NCT04194281

Feasibility of Action Observation Training [AOT] in Infants After Unilateral Brain Lesion

Completed NA Last updated 6 October 2021

What this trial tests

NA trial testing Action Observation Training [AOT] in Perinatal Brain Injury in 8 participants. Completed in 30 July 2021.

Timeline

30 May 2020

Primary endpoint
30 July 2021

30 July 2021

Quick facts

Lead sponsor	Insel Gruppe AG, University Hospital Bern
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	8
Start date	30 May 2020
Primary completion	30 July 2021
Estimated completion	30 July 2021
Sites	1 location across Switzerland

Drugs / interventions tested

• Action Observation Training [AOT]

Conditions studied

• Perinatal Brain Injury — all drugs for Perinatal Brain Injury →

Sponsor

Insel Gruppe AG, University Hospital Bern

Who can join

Adults 9 Months to 12 Months, any sex, with Perinatal Brain Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study examines whether infants with a perinatal unilateral brain lesion can perform an "Action Observation Training" \[AOT\] at the age of 9-12 months . AOT is the targeted and concentrated observation of movements and actions to learn new motor skills. In adults with hemiplegia after a stroke and in older children with hemiplegia, AOT can lead to an improvement in the functions of the affected hand/arm. Infants with early unilateral brain damage are at increased risk of developing a hemiplegia and thus impaired upper limb function. There is little known about treatment options to promote arm and hand skills in early childhood and their effectiveness. In particular, there is a lack of knowledge whether AOT could also be used in infants. It is known that even in infants at an early age brain activity can be measured while they are observing movements and infants learn a lot about observing and imitating.

Knowledge about the measurement of manual skills is also reduced. So far, tests have been used to observe and evaluate how infants use their hands when playing (e.g. Mini-Assisting Hand Assessment). The aim of this study is to investigate whether measurements with motion sensors can also be used in infants.

In the pre-post study, about 5 to 10 toddlers will be examined. During four weeks, the parents should give the child 20 minutes of AOT per day at home. A therapy diary will be completed for this purpose. During six weeks, the parents will use movement sensors on two days a week for the upper limb of the infants. Finally, three questionnaires about the AOT and the motion sensors will be completed by the parents.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.