NCT04193371 (PCOS) is a NA clinical trial of Active acupuncture in PCOS, sponsored by Peking University Third Hospital.

Who is sponsoring NCT04193371?

NCT04193371 is sponsored by Peking University Third Hospital.

What drugs are being tested in NCT04193371?

Interventions in NCT04193371: Active acupuncture, Sham acupuncture, Lifestyle management.

What condition does NCT04193371 study?

NCT04193371 studies PCOS, Overweight, Obesity.

Is NCT04193371 still recruiting?

NCT04193371 is currently completed. Last updated 22 June 2025.

Last reviewed 2025-06-22 · How we verify

NCT04193371: PCOS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Acupuncture on Body Mass Index in Overweight and Obese Women With Polycystic Ovary Syndrome (PCOS )

Completed NA Last updated 22 June 2025

What this trial tests

NA trial testing Active acupuncture in PCOS in 106 participants. Completed in 31 December 2024.

Timeline

6 December 2019

Primary endpoint
1 December 2024

31 December 2024

Quick facts

Lead sponsor	Peking University Third Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	106
Start date	6 December 2019
Primary completion	1 December 2024
Estimated completion	31 December 2024
Sites	1 location across China

Drugs / interventions tested

Active acupuncture
Sham acupuncture
Lifestyle management — full drug profile →

Conditions studied

PCOS — all drugs for PCOS →
Overweight — all drugs for Overweight →
Obesity — all drugs for Obesity →

Sponsor

Peking University Third Hospital

Who can join

Adults 20 to 40, female only, with PCOS or Overweight. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a cross-sectional case-control study combined with a randomised controlled trial (RCT) study. This study aims to compare the effect of acupuncture, with usual care (lifestyle management) for weight control, with BMI (Body Mass index) as main outcome along with improvement of reproductive and metabolic dysfunction in overweight and obese women with PCOS, and further exploring the alteration of lipidomics, bile acid omics, proteomics and branched-chain amino acids between PCOS and the normal controls, and before and after the acupuncture treatment in different gourps.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Acupuncture of polycystic ovary syndrome: delving into bile acid metabolism.
Zhang H, Chen Y, Heng D, Luo J, et al · · 2026 · PMID 41514462 · DOI 10.1186/s13020-025-01297-6
Clinical symptom improvement and lipidomic signatures in overweight/obese PCOS treated by lifestyle and acupuncture intervention.
Zhang H, Tian W, Li D, Chen Y, et al · · 2025 · PMID 41210858 · DOI 10.3389/fmed.2025.1642095
Acupuncture of Polycystic Ovary Syndrome: Delving into Bile Acid Metabolism
Zhang H, Chen Y, Heng D, Luo J, et al · · 2025 · DOI 10.21203/rs.3.rs-6600841/v1

Verify or expand the search:

Other trials of Active acupuncture

Trials testing the same drug.

NCT05078944 — Progress of Mild Alzheimer's Disease in Participants on Acupuncture Versus Sham Acupuncture · NA · completed
NCT04401384 — Effectiveness of Acupuncture and Doxylamine/Pyridoxine for Moderate to Severe Nausea and Vomiting in Pregnancy · Phase 3 · completed

Other recruiting trials for PCOS

Currently open trials in the same condition.

NCT06424860 — Fish Oil, Metformin and Heart Health in PCOS · Phase 1 · recruiting
NCT06742710 — Liraglutide Treatment in Obese Infertile PCOS Women · Phase 4 · recruiting
NCT07255911 — Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS · NA · recruiting
NCT06793072 — Adipokines in Polycystic Ovary Syndrome · recruiting
NCT06591169 — Lifestyle Changes in PCOS with OSA and NAFLD · NA · recruiting

Other Peking University Third Hospital trials

Trials by the same sponsor.

NCT07532421 — Probiotic Intervention on the Development of Allergic Diseases in Infants Exposed to Antibiotics Early in Life · NA · not yet recruiting
NCT07470255 — Detection of Diabetic Foot Skin Damage Using Plantar Mechanical Parameters · not yet recruiting
NCT07453381 — Multisensor Wireless Pressure Microcatheter For Microvascular Function Assessment In ANOCA/INOCA Patients: A Prospective · not yet recruiting
NCT07452354 — AI-Based Diabetic Foot Recurrence Cohort · not yet recruiting
NCT07423819 — Sports Rehabilitation Therapy for Knee Joint Sports Injuries: A Case Study of Anterior Cruciate Ligament Injury and Pate · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04193371 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Peking University Third Hospital
Last refreshed: 22 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04193371.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing