Last reviewed · How we verify
NCT04191915
Frailty Assessment in Cardiac Surgery
trial in Frailty in 164 participants. Completed in 15 June 2020.
15 May 2020
Quick facts
| Lead sponsor | Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 164 |
| Start date | 15 January 2020 |
| Primary completion | 15 May 2020 |
| Estimated completion | 15 June 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Frailty — all drugs for Frailty →
Sponsor
Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Who can join
65 and older, any sex, with Frailty. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
With increasing life expectancy, cardiac surgical procedures are increasingly being performed in older adults. The biological syndrome of frailty is an aging-associated state with diminished physiological reserve and resistance to stressors, such as major surgery. In the European System for Cardiac Operative risk Evaluation (EuroSCORE II) and the Society of Thoracic Surgeons (STS) risk scoring systems, patient comorbidities including advanced age and poor mobility are considered as risk factors for operative mortality. However, an objective assessment of frailty is not included. Traditionally, frailty assessment before cardiac surgery is primarily performed based on surgeon's subjective perception of patient's general appearance. Objective measurement of frailty is increasingly being applied as a routine part of preoperative evaluation of elderly patients undergoing cardiac surgery. The most widely used frailty assessment tool is the Fried scale. The investigators aim to investigate whether Fried scale would predict operative mortality and morbidity in elderly patients undergoing elective cardiac surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Frailty Assessment to Improve Risk Stratification in Elderly Patients Undergoing Elective Cardiac Surgery.
Ozeren K, Topcu AC, Kayacioglu I. · · 2025 · PMID 40101125 · DOI 10.21470/1678-9741-2023-0182
Verify or expand the search:
- PubMed search for NCT04191915
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital trials
Trials by the same sponsor.
- NCT05603429 — Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery · completed
- NCT04755439 — Evaluation of Cerebral Parenchymal Changes in Patients Undergoing Proximal Aortic Surgery With Deep Hypothermic Circulat · NA · completed
- NCT04879550 — Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO · completed
- NCT04990700 — Effect of Partial Rib Resection On the Control of Post-thoracotomy Pain · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04191915 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
- Last refreshed: 4 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04191915.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing