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NCT04191772: EXIMS
The Impact of Training on Sitting Time and Brain Volumes in Multiple Sclerosis.
NA trial testing Periodized, home-based running program in Multiple Sclerosis in 156 participants. Completed in 30 June 2021.
30 June 2021
Quick facts
| Lead sponsor | Hasselt University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 156 |
| Start date | 15 January 2020 |
| Primary completion | 30 June 2021 |
| Estimated completion | 30 June 2021 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Periodized, home-based running program
Conditions studied
- Multiple Sclerosis — all drugs for Multiple Sclerosis →
Sponsor
Hasselt University
Who can join
18 and older, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The current study aims to investigate whether persons with Multiple Sclerosis (PwMS) compensate training time with more sedentary time and consequently blunt training effects. The second aim will be to investigate the effect of a structured training program on specific brain volumes and cognitive variables.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The effect of a structured running exercise intervention on non-exercise physical activity and sedentary behaviour in persons with mild Multiple Sclerosis and healthy controls.
Nieste I, Spaas J, Franssen WMA, Asch PV, et al · · 2023 · PMID 40217416 · DOI 10.1186/s44167-023-00037-1 -
The effect of structured exercise on non-exercise physical activity and sedentary behaviour in persons with mild Multiple Sclerosis and healthy controls
Nieste I, Spaas J, Franssen WM, Asch PV, et al · · 2023 · DOI 10.21203/rs.3.rs-3203061/v1
Verify or expand the search:
- PubMed search for NCT04191772
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Multiple Sclerosis
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Other Hasselt University trials
Trials by the same sponsor.
- NCT07419100 — Sedentary Behaviour, Physical Activity Patterns, and Cardiometabolic Health · NA · not yet recruiting
- NCT07505355 — Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis · recruiting
- NCT07081893 — How do Patients, Relatives and Healthcare Professionals View Person-centered Rehabilitation. · not yet recruiting
- NCT06785909 — Proprioceptive, Fear-related and Inflammatory Factors in the Persistence of Pregnancy-related Lumbopelvic Pain. · NA · recruiting
- NCT07175792 — Accuracy of Motor Performance Perception in Multiple Sclerosis · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04191772 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hasselt University
- Last refreshed: 31 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04191772.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing