Who is sponsoring NCT04184999?

NCT04184999 is sponsored by SR Cornea Consultants.

What drugs are being tested in NCT04184999?

Interventions in NCT04184999: dexamethasone intraocular suspension, 9%, Prednisolone Acetate 1% Oph Susp.

What condition does NCT04184999 study?

NCT04184999 studies Dry Eye Syndromes.

Is NCT04184999 still recruiting?

NCT04184999 is currently completed. Last updated 22 November 2023.

Are results published for NCT04184999?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-11-22 · How we verify

NCT04184999

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Intraoperative Dexamethasone on Post-op Dry Eye

Completed Phase 4 Results posted Last updated 22 November 2023

What this trial tests

Phase 4 trial testing dexamethasone intraocular suspension, 9% in Dry Eye Syndromes in 40 participants. Completed in 1 December 2019.

Timeline

10 August 2019

Primary endpoint
1 December 2019

1 December 2019

Quick facts

Lead sponsor	SR Cornea Consultants
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	40
Start date	10 August 2019
Primary completion	1 December 2019
Estimated completion	1 December 2019
Sites	1 location across United States

Drugs / interventions tested

dexamethasone intraocular suspension, 9% — full drug profile →
Prednisolone Acetate 1% Oph Susp — full drug profile →

Conditions studied

Dry Eye Syndromes — all drugs for Dry Eye Syndromes →

Sponsor

SR Cornea Consultants — full company profile →

Who can join

Adults 18 to 90, any sex, with Dry Eye Syndromes. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Evaluation of Intraoperative Use of Dexycu on Tear Film Osmolarity at 3 Weeks Postoperatively Primary · 3 weeks

Tear Film Osmolarity as measured on Tear Lab system; validated measure of Tear Film Osmolarity Osmolarity was reported in milliosmoles per liter (mOsmol/L)

Group	Value	95% CI
Intracameral Dexamethasone	311.15	284 – 333
Postoperative Prednisolone Acetate	316.3	286 – 335

Sponsor's own description

To compare the signs and symptoms of dry eye after cataract surgery between subjects randomized to receive intraoperative dexamethasone in addition to the use of a standard topical post-op treatment regimen.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Dry Eye Syndromes

Currently open trials in the same condition.

NCT07412860 — Clinical Investigation Between the Topical Administration of a Tear Substitute With Ancillary Medicinal Substance and Hy · NA · recruiting
NCT06913504 — Comparison Of Blue Light Filter Feature and Blue Blocking Lenses in Digital Device Users With Dry Eye Patients · NA · active not recruiting
NCT06913465 — The Impact of Hypothyroidism on Tear Production and Dry Eye Symptoms: Implications for Optometric Care · active not recruiting
NCT06831253 — Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome · NA · recruiting
NCT06220474 — Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04184999 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by SR Cornea Consultants
Last refreshed: 22 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04184999.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing