NCT04184544: UeN

Scaling up Evidence Based MNCH Interventions : A Quasi Experimental Study Umeed e Nau (UeN) Project

Status unknown NA Last updated 1 September 2021

What this trial tests

NA trial testing Improving of quality of care at health facility and outreach level in Maternal Complication of Pregnancy in 5,000,000 participants. Status unknown.

Timeline

1 March 2017

Primary endpoint
31 December 2022

30 June 2023

Quick facts

Lead sponsor	Aga Khan University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	non randomized
Design	factorial
Masking	none
Primary purpose	health services research
Enrollment	5,000,000
Start date	1 March 2017
Primary completion	31 December 2022
Estimated completion	30 June 2023
Sites	1 location across Pakistan

Drugs / interventions tested

• Improving of quality of care at health facility and outreach level

Conditions studied

• Maternal Complication of Pregnancy — all drugs for Maternal Complication of Pregnancy →
• Newborn Morbidity — all drugs for Newborn Morbidity →
• Perinatal Problems — all drugs for Perinatal Problems →

Sponsor

Aga Khan University

Who can join

Eligibility, any sex, with Maternal Complication of Pregnancy or Newborn Morbidity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Umeed-e-Nau (UeN) initiative aims to support the introduction, scale up, and further piloting of high quality and high impact interventions to improve Maternal, Newborn And Child Health (MNCH)in Pakistan by harnessing the potential of both public and private sectors, coupled with introduction of women and girls empowerment interventions. UeN has two major components: 1) Introducing proven effective MNCH interventions at scale in 8 rural districts of Pakistan, and 2) Generating evidence on innovative approaches to improve MNCH while included in public health programs in Pakistan. There are six trials that are being conducted to address different evidences gaps to improve maternal, newborn and child health in Pakistan. The protocols of the trials will be registered separately.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

1. Predictors and disparities in neonatal and under 5 mortality in rural Pakistan: cross sectional analysis.
   Memon Z, Fridman D, Soofi S, Ahmed W, et al · · 2023 · cited 15× · PMID 37614356 · DOI 10.1016/j.lansea.2023.100231
2. Effect and feasibility of district level scale up of maternal, newborn and child health interventions in Pakistan: a quasi-experimental study.
   Memon ZA, Muhammad S, Soofi S, Khan N, et al · · 2020 · cited 4× · PMID 32665387 · DOI 10.1136/bmjopen-2019-036293
3. A cross-sectional analysis of the impact of lady health worker visits in the prenatal and postnatal period on the uptake of continuum of care interventions and childhood mortality in Pakistan.
   Muhammad S, Memon ZA, Mian A, Wasan Y, et al · · 2025 · cited 2× · PMID 40452336 · DOI 10.7189/jogh.15.04158
4. Clinical Trials and Therapeutic Approaches for Healthcare Challenges in Pakistan
   Ahmed A, Williams N. · · 2023