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NCT04183218
Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes
trial testing Biospecimen Collection in Clinical Stage 0 Esophageal Adenocarcinoma AJCC V8 in 24 participants. Completed in 2 May 2024.
6 January 2024
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 24 |
| Start date | 23 September 2019 |
| Primary completion | 6 January 2024 |
| Estimated completion | 2 May 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Biospecimen Collection — full drug profile →
- Cardiac Event Monitor
- Chemoradiotherapy — full drug profile →
- Radiation Therapy — full drug profile →
Conditions studied
- Clinical Stage 0 Esophageal Adenocarcinoma AJCC V8 — all drugs for Clinical Stage 0 Esophageal Adenocarcinoma AJCC V8 →
- Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC V8 — all drugs for Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC V8 →
- Clinical Stage I Esophageal Adenocarcinoma AJCC V8 — all drugs for Clinical Stage I Esophageal Adenocarcinoma AJCC V8 →
- Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC V8 — all drugs for Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC V8 →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Clinical Stage 0 Esophageal Adenocarcinoma AJCC V8 or Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC V8. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial studies cardiac changes after radiation or chemo-radiation for the treatment of lung or esophageal cancer that has not spread to other places in the body (non-metastatic) or has not come back (non-recurrent). Continuous cardiac monitoring with an implanted device may help to identify cardiac changes that would remain unnoticed, and facilitate the treatment of these early cardiac changes as part of standard care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04183218
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Mayo Clinic trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04183218 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 23 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04183218.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing