NCT04180137 is a NA clinical trial of Endovenous laser ablation of great saphenous vein (GSV) and microphlebectomy of varicose veins in Venous Insufficiency of Leg, sponsored by State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia.

What condition does NCT04180137 study?

NCT04180137 studies Venous Insufficiency of Leg, Venous Insufficiency (Chronic)(Peripheral), Endothelial Dysfunction.

Is NCT04180137 still recruiting?

NCT04180137 is currently completed. Last updated 13 September 2021.

Last reviewed 2021-09-13 · How we verify

NCT04180137

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Management of Endothelial Dysfunction in Patients With Chronic Venous Insufficiency After Endovenous Surgical Procedure

Completed NA Last updated 13 September 2021

What this trial tests

NA trial testing Endovenous laser ablation of great saphenous vein (GSV) and microphlebectomy of varicose veins in Venous Insufficiency of Leg in 40 participants. Completed in 30 July 2021.

Timeline

28 November 2019

Primary endpoint
31 December 2020

30 July 2021

Quick facts

Lead sponsor	State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	basic science
Enrollment	40
Start date	28 November 2019
Primary completion	31 December 2020
Estimated completion	30 July 2021
Sites	1 location across Russia

Drugs / interventions tested

Endovenous laser ablation of great saphenous vein (GSV) and microphlebectomy of varicose veins
Pharmacotherapy — full drug profile →

Conditions studied

Venous Insufficiency of Leg — all drugs for Venous Insufficiency of Leg →
Venous Insufficiency (Chronic)(Peripheral) — all drugs for Venous Insufficiency (Chronic)(Peripheral) →
Endothelial Dysfunction — all drugs for Endothelial Dysfunction →

Sponsor

State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia

Who can join

Adults 18 to 65, any sex, with Venous Insufficiency of Leg or Venous Insufficiency (Chronic)(Peripheral). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Endothelial dysfunction is assessed in patients with chronic venous insufficiency of lower limbs (grade C4 according to C - clinical manifestations, E - etiologic factors, A - anatomic distribution of disease, and P - underlying pathophysiologic findings (CEAP) classification) prior to and after endovenous surgical procedure, i.e. endovenous laser ablation of great saphenous vein, microphlebectomy of varicose branches. Two treatment groups (with and without additional pharmacotherapy) are compared.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Venous Insufficiency of Leg

Currently open trials in the same condition.

NCT06711120 — Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous V · NA · recruiting
NCT06693245 — Observation of Pain During the Treatment of Great Saphenous Vein Using Microwave Ablation， and Analysis of Related Facto · recruiting
NCT06366763 — Comparative Clinical Efficacy Between Multi-layer Bandage Pressure Therapy and Gradient Pressure Elastic Stocking Treatm · NA · recruiting

Other State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia trials

Trials by the same sponsor.

NCT07211074 — Optimal PEEP Level for Minimizing the Risk of Postoperative Atelectasis: A Retrospective Cohort Study Based on Lung Ultr · completed
NCT07061223 — SFIB vs PENG Block in the Anesthesia for Total Hip Replacement · NA · enrolling by invitation
NCT07059429 — Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee Arthroplasty · NA · completed
NCT05814991 — A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthogna · enrolling by invitation
NCT05248269 — Thermocoagulation in Drug Resistant Focal Epilepsy · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04180137 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Last refreshed: 13 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04180137.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing